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由萨氏毛霉引起的致命性原发性皮肤毛霉病:病例报告及文献复习。

Fatal primary cutaneous zygomycosis caused by Saksenaea vasiformis: case report and review of literature.

机构信息

Department of General Surgery, Government Medical College Hospital, Chandigarh, India.

出版信息

Surg Infect (Larchmt). 2012 Apr;13(2):125-9. doi: 10.1089/sur.2010.078. Epub 2012 Jan 26.

DOI:10.1089/sur.2010.078
PMID:22280152
Abstract

BACKGROUND

Primary cutaneous zygomycosis caused by Saksenaea vasiformis is rare. Such infections usually are not suspected, and delay in their diagnosis and treatment results in a poor outcome.

METHODS

Case report and review of the relevant English-language literature.

RESULTS

A fulminant cutaneous infection developing after intramuscular injection in the gluteal region of a 60-year-old female patient is described. The hallmark of this uncommon infection was the rapidity with which the skin and subcutaneous tissues of the right gluteal and lower abdominal regions underwent necrosis. The infection remained undiagnosed for nearly two weeks, leading to a fatal outcome.

CONCLUSION

Awareness of the fact that fungi can also be the cause of cutaneous infections, as well as a high index of suspicion in patients who do not respond to conventional therapy, should help in the early diagnosis and management of such infections and may help in reducing the mortality rate.

摘要

背景

由萨氏毛霉引起的原发性皮肤毛霉病较为罕见。此类感染通常不会被怀疑,诊断和治疗的延迟会导致不良后果。

方法

病例报告并回顾相关的英文文献。

结果

描述了一位 60 岁女性患者在臀部肌肉注射后发生的暴发性皮肤感染。这种罕见感染的特点是右侧臀部和下腹部的皮肤和皮下组织迅速坏死。感染近两周未被诊断,导致了致命的结果。

结论

认识到真菌也可能是皮肤感染的原因,以及对常规治疗无反应的患者保持高度怀疑,有助于早期诊断和治疗此类感染,并可能有助于降低死亡率。

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