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通过离子电渗疗法运载的预制生长因子对雄激素性脱发和休止期脱发患者的有效性和耐受性:一项临床研究。

The Effectiveness and Tolerability of Preformed Growth Factors Vehiculated Through Iontophoresis on Patients with Androgenetic Alopecia and Telogen Effluvium: A Clinical Study.

作者信息

Alessandrini Aurora Maria, Bruni Francesca, Piraccini Bianca Maria, Starace Michela

机构信息

Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.

出版信息

Dermatol Pract Concept. 2021 May 20;11(3):e2021082. doi: 10.5826/dpc.1103a82. eCollection 2021 May.

Abstract

BACKGROUND

Androgenetic alopecia is characterized by a progressive miniaturization of hair follicles in a pattern distribution in genetically predisposed individuals. The efficacy of conventional therapies is variable, therefore there is a need for adjuvant and newer treatment modalities to provide faster and better outcomes.

OBJECTIVES

Evaluation of vehiculated through iontopthheo ereffsiicsa icny paantdie tnotlse rwaibtihli tayn odfr ao gceonmebtiicn aeldo tpheecriaap ayn: dp raesfsoorcmiaetded g rteolwogthe nfa ecftfolursvium, to obtain faster hair regrowth.

MATERIALS AND METHODS

Treatment was performed between June 2018 and June 2019 on 60 patients with androgenetic alopecia and associated telogen effluvium. Each patient underwent 4 sessions in total, each session was performed every 3 weeks. Global photography and trichoscopy were collected at every session of therapy. All patients filed out a self-assessment questionnaire.

RESULTS

Results were very promising, with improvement of hair density and thickening of the hair shaft diameter in most of patients seen with both global photography and trichoscopy. All patients were satisfied of the clinical result and reported a complete reduction in hair loss. No serious adverse side effects were reported.

CONCLUSIONS

The use of growth factors associated with iontophoresis technique is a useful treatment for treating and preventing androgenetic alopecia. In addition, in case of associated telogen effluvium, this technique allows for an early stop of hair shedding, especially when cosmetic procedures do not provide satisfactory results in patients.

摘要

背景

雄激素性脱发的特征是在遗传易感性个体中,毛囊以特定模式分布进行性变小。传统疗法的疗效不一,因此需要辅助和更新的治疗方式以获得更快更好的效果。

目的

评估通过离子导入技术运载生长因子对雄激素性脱发伴休止期脱发患者的疗效:促进毛囊生长,以更快地促进头发生长。

材料和方法

2018年6月至2019年6月对60例雄激素性脱发伴休止期脱发患者进行治疗。每位患者共接受4次治疗,每次治疗间隔3周。每次治疗时均采集整体照片和毛发镜图像。所有患者均填写了自我评估问卷。

结果

结果非常令人满意,通过整体照片和毛发镜检查可见大多数患者的头发密度增加,毛干直径变粗。所有患者对临床结果均满意,并报告脱发完全减少。未报告严重不良副作用。

结论

使用与离子导入技术相关的生长因子是治疗和预防雄激素性脱发的有效方法。此外,对于伴有休止期脱发的情况,该技术可使脱发提前停止,尤其是在美容手术对患者效果不佳时。

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