卡介苗对新冠病毒感染死亡率的保护作用差异：一项全球评估。
Variances in BCG protection against COVID-19 mortality: A global assessment.
作者信息
Sarfraz Zouina, Sarfraz Azza, Pandav Krunal, Singh Makkar Sarabjot, Hasan Siddiqui Saman, Patel Gaurav, Platero-Portillo Tania, Singh Bishnu Mohan, Maideen Mohamed Iburahim Haja, Sarvepalli Deepika, Sarfraz Muzna, Cardona-Guzman Jose, Sanchez-Gonzalez Marcos A, Cherrez-Ojeda Ivan
机构信息
Division of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Department of Research & Publication, Fatima Jinnah Medical University, Lahore, Pakistan.
出版信息
J Clin Tuberc Other Mycobact Dis. 2021 Aug;24:100249. doi: 10.1016/j.jctube.2021.100249. Epub 2021 Jun 6.
The BCG vaccine is known to impart nonspecific immunological benefits alongside conferring protection to tuberculosis in endemic regions. It is also known to protect against bladder cancer and other respiratory tract infections. During the coronavirus disease 2019 (COVID-19) pandemic, the BCG vaccine has gained attention due to its role in conferring protective immunity. We demonstrate the potential immunological protective mechanisms that play a role against COVID-19. We conduct a global assessment of the countries that have the highest and lowest mortality rates determined by an a priori methodology. Lastly, we discuss the potential limitations of incorporating BCG vaccines as potential strategies against COVID-19 and provide recommendations regarding their use in ongoing and future epidemics.
众所周知，卡介苗（BCG）疫苗在流行地区预防结核病的同时，还能带来非特异性免疫益处。它还能预防膀胱癌和其他呼吸道感染。在2019年冠状病毒病（COVID-19）大流行期间，卡介苗疫苗因其在提供保护性免疫方面的作用而受到关注。我们展示了对COVID-19起作用的潜在免疫保护机制。我们对通过先验方法确定的死亡率最高和最低的国家进行了全球评估。最后，我们讨论了将卡介苗疫苗作为对抗COVID-19的潜在策略的潜在局限性，并就其在当前和未来疫情中的使用提供建议。
Zotero 插件