Morimoto Yasuo, Nishida Chinatsu, Tomonaga Taisuke, Izumi Hiroto, Yatera Kazuhiro, Sakurai Kazuo, Kim Yangho
Department of Occupational Pneumology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan.
Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
J Occup Health. 2021 Jan;63(1):e12240. doi: 10.1002/1348-9585.12240.
Respirable organic chemicals were originally thought to cause allergic respiratory diseases, such as bronchial asthma and hypersensitivity pneumonitis, and believed not to cause lung disorders derived from inflammatory or fibrotic processes such as pulmonary fibrosis and interstitial pneumonitis. It has recently been reported, however, that exposure to organic chemicals can cause interstitial lung diseases. In this review, we discuss the clinical features of occupational asthma and hypersensitivity pneumonitis, as well as other lung disorders, including interstitial pneumonitis, caused by humidifier disinfectants in Korea and by a cross-linked acrylic acid-based polymer (CL-PAA) in Japan.
可吸入有机化学物质最初被认为会引发过敏性呼吸道疾病，如支气管哮喘和过敏性肺炎，并且人们认为它们不会导致由炎症或纤维化过程引起的肺部疾病，如肺纤维化和间质性肺炎。然而，最近有报道称，接触有机化学物质会导致间质性肺病。在这篇综述中，我们讨论了职业性哮喘和过敏性肺炎的临床特征，以及在韩国由加湿器消毒剂和在日本由一种交联丙烯酸基聚合物（CL-PAA）引起的其他肺部疾病，包括间质性肺炎。
