Mannino D, Geiss R, Hodous T, Lapp N L
Critical Care Medicine, West Virginia University School of Medicine, Morgantown, USA.
South Med J. 1996 Sep;89(9):898-901. doi: 10.1097/00007611-199609000-00011.
A 44-year-old farmer had respiratory symptoms and bibasilar pulmonary infiltrates after three exposures to a new biologic forage inoculant. Open lung biopsy revealed chronic interstitial pneumonitis and bronchiolitis obliterans with organizing pneumonia. The patient responded to oral corticosteroids but acutely worsened after an inadvertent reexposure to the forage inoculant. He later recovered, with return of lung function and chest radiograph toward normal. This case suggests that biologic forage inoculants may be associated with hypersensitivity pneumonitis.
一名44岁的农民在三次接触一种新型生物饲料接种剂后出现呼吸道症状和双肺底部肺部浸润。开胸肺活检显示为慢性间质性肺炎和闭塞性细支气管炎伴机化性肺炎。患者对口服皮质类固醇有反应,但在意外再次接触饲料接种剂后病情急性恶化。他后来康复,肺功能和胸部X光片恢复正常。该病例提示生物饲料接种剂可能与过敏性肺炎有关。