Department of Psychiatry and Behavioral Medicine, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Department of Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Obesity (Silver Spring). 2021 Aug;29(8):1239-1241. doi: 10.1002/oby.23187. Epub 2021 Jun 14.
Bariatric surgery has been shown to improve cognition in patients with severe obesity. Bariatric surgery may improve mental function in patient populations with obesity and with cognitive impairment, including nonacquired, dementia, and traumatic brain injury, although studies have been limited. Bariatric surgery provides an opportunity to explore the effects of obesity, type 2 diabetes, dyslipidemias, and other expressions of metabolic syndrome on cognition. It offers the unusual opportunity to study patients with these chronic diseases and, later, those without them. This suggests the need for further studies into the effects of bariatric surgery on patient populations with obesity and with cognitive impairment to look at the effects of the continuing metabolic brain damage in people with severe obesity when earlier intervention could be considered.
减重手术已被证明可改善重度肥胖患者的认知功能。减重手术可能会改善肥胖和认知障碍患者人群的精神功能，包括非获得性痴呆和创伤性脑损伤，但研究有限。减重手术为探索肥胖、2 型糖尿病、血脂异常和其他代谢综合征表现对认知的影响提供了机会。它为研究患有这些慢性疾病的患者，以及以后没有这些疾病的患者提供了一个不同寻常的机会。这表明需要进一步研究减重手术对肥胖和认知障碍患者人群的影响，以观察在考虑早期干预时严重肥胖人群持续代谢性脑损伤的影响。
