Department of Pathology, Medical University Vienna, Vienna General Hospital.
Department of Pathology, Hôpital Tenon, Sorbonne University.
Adv Anat Pathol. 2021 Jul 1;28(4):196-208. doi: 10.1097/PAP.0000000000000309.
The Genitourinary Pathology Society (GUPS) undertook a critical review of the recent advances in bladder cancer focusing on important topics of high interest for the practicing surgical pathologist and urologist. This review represents the second of 2 manuscripts ensuing from this effort. Herein, we address the effective reporting of bladder cancer, focusing particularly on newly published data since the last 2016 World Health Organization (WHO) classification. In addition, this review focuses on the importance of reporting bladder cancer with divergent differentiation and variant (subtypes of urothelial carcinoma) histologies and the potential impact on patient care. We provide new recommendations for reporting pT1 staging in diagnostic pathology. Furthermore, we explore molecular evolution and classification, emphasizing aspects that impact the understanding of important concepts relevant to reporting and management of patients.
泌尿生殖系统病理学学会（GUPS）对膀胱癌的最新进展进行了批判性回顾，重点关注对执业外科病理学家和泌尿科医生有高度兴趣的重要课题。这篇综述是这项工作的后续 2 篇文章中的第 2 篇。在这里，我们重点关注膀胱癌的有效报告，特别是自上次 2016 年世界卫生组织（WHO）分类以来新发表的数据。此外，本综述还重点关注报告分化和变异（尿路上皮癌的亚型）组织学的膀胱癌的重要性，以及对患者护理的潜在影响。我们为诊断病理学中的 pT1 分期报告提供了新的建议。此外，我们探讨了分子进化和分类，强调了影响报告和管理患者的重要概念理解的方面。
