Microplastics (MPs) pollution has become a global environmental concern because of their severe threat to biota. However, limited studies on the elimination of MPs pollution were reported. The conventional treatment methods were not suitable for MPs owing to their smaller size than plastic items. Hence many methods for MPs treatment have been examined. This review summarized the recently reported MPs degradation methods including AOPs (direct photodegradation, photocatalytic oxidation, and electrochemical oxidation) and biodegradation, corresponding degradation mechanism as well as current development state. The characteristics and limitations of each technique were discussed in detail. We found that all of them achieved almost satisfying degradation performance of MPs, but most of them exhibited that MPs can only be degraded partially into useful products or even CO and HO under lab conditions. Given these, some recommendations for future research directions were proposed based on the knowledge gaps in these reported literatures. The aim of this review is to give a comprehensive introduction of several MPs degradation methods and acquaint the readers with the current research status of MPs degradation.