Department of Pediatric Hematology and Oncology, Medical University of Gdańsk, Gdańsk, Poland.
J Pediatr Hematol Oncol. 2022 Mar 1;44(2):e543-e545. doi: 10.1097/MPH.0000000000002229.
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus-2. Patients with hematologic malignancies have been shown to have higher risk of mortality due to COVID-19 than reported in the general adult population. Reports on acute lymphoblastic leukemia and COVID in children are scarce. We present a case of an 11-year-old male patient undergoing treatment for B-cell acute lymphoblastic leukemia with an atypical course of COVID-19. The patient received a positive result of the syndrome coronavirus-2 polymerase chain reaction test performed due to epidemiologic reasons. The chemotherapy was continued since the patient had no clinical signs of COVID-19. The disease started with intensive gastrointestinal bleeding, followed by severe respiratory tract infection over 2 weeks later.
2019 年冠状病毒病(COVID-19)是由严重急性呼吸系统综合征冠状病毒 2 引起的传染病。与一般成年人群相比,患有血液系统恶性肿瘤的患者因 COVID-19 而死亡的风险更高。关于儿童急性淋巴细胞白血病和 COVID 的报告很少。我们报告了一例 11 岁男性患者,该患者正在接受 B 细胞急性淋巴细胞白血病治疗,其 COVID-19 的病程不典型。由于流行病学原因,该患者进行了综合征冠状病毒-2 聚合酶链反应检测,结果呈阳性。由于该患者没有 COVID-19 的临床症状,因此继续进行化疗。疾病首先表现为严重的胃肠道出血,两周后又出现严重的呼吸道感染。