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近期感染 SARS-CoV-2 后继发的小儿急性 B 细胞淋巴细胞白血病。

Pediatric Acute B-Cell Lymphoblastic Leukemia Developing Following Recent SARS-CoV-2 Infection.

机构信息

Children's Hospital of Geneva.

Paediatric Oncology and Hematology Unit.

出版信息

J Pediatr Hematol Oncol. 2021 Nov 1;43(8):e1177-e1180. doi: 10.1097/MPH.0000000000002064.

Abstract

Coronavirus disease-2019 in children has been linked to various clinical presentation, from paucisymptomatic cutaneous eruptions, to multisystemic inflammatory syndrome. We report the case of an 8-year-old boy who presented with persistent fever and pancytopenia, associated to a skin rash. An extensive etiological workup showed a positive serology for severe acute respiratory syndrome coronavirus 2 and Epstein-Barr virus. A few weeks later, type B acute lymphocytic leukemia was diagnosed. This case underlines the polymorphic appearance of coronavirus disease-2019 and the need for critical appraisal.

摘要

儿童 2019 冠状病毒病与各种临床表现相关,从症状轻微的皮肤疹,到多系统炎症综合征。我们报告了一例 8 岁男孩的病例,他表现为持续发热和全血细胞减少,并伴有皮疹。广泛的病因学检查显示严重急性呼吸综合征冠状病毒 2 和 Epstein-Barr 病毒的血清学呈阳性。几周后,诊断出 B 型急性淋巴细胞白血病。本病例强调了 2019 冠状病毒病的多态性表现,需要进行批判性评估。

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