Department of Sociology and Yale Institute for Network Science, Yale University, 17 Hillhouse Ave, New Haven, CT 06520, United States of America.
Yale Institute for Network Science, Yale University, United States of America.
J Subst Abuse Treat. 2021 Aug;127:108367. doi: 10.1016/j.jsat.2021.108367. Epub 2021 Mar 16.
Social connections can lead to contagion of healthy behaviors. Successful treatment of patients with opioid use disorder may lay in rebuilding social networks. Strong social networks of support can reinforce the benefits of medication treatments that are the current standard of care and the most effective tool physicians have to fight the opioid epidemic.
The research team conducted a systematic review of electronic research databases, specialist journals and grey literature up to August 2020 to identify randomized controlled trials of social network support in patient populations receiving medication for opioid use disorder (MOUD). The research team placed the studies into a framework of dynamic social networks, examining the role of networks before MOUD treatment is initiated, during the treatment, and in the long-term following the treatment. The research team analyzed the results across three sources of social network support: partner relationships, family, and peer networks.
Of 5193 articles screened, eight studies were identified as meeting inclusion criteria. Five studies indicated that social network support had a statistically significant effect on improved MOUD treatment outcomes. We find the strongest support for the positive impact of family social network support.
Social networks significantly shape effectiveness of opioid use disorder treatments. While negative social ties reinforce addiction, positive social support networks can amplify the benefits of medication treatments. Targeted interventions to improve treatment outcomes can be designed and added to MOUD treatment with their effects evaluated in improving patients' odds of recovery from opioid use disorder and reversing the rising trend in opioid deaths.
社会关系可以导致健康行为的传播。成功治疗阿片类药物使用障碍患者可能在于重建社交网络。强大的支持社交网络可以强化药物治疗的益处,药物治疗是当前的标准护理,也是医生对抗阿片类药物流行的最有效工具。
研究团队对电子研究数据库、专业期刊和灰色文献进行了系统回顾,截至 2020 年 8 月,以确定接受药物治疗阿片类药物使用障碍(MOUD)的患者人群中社会网络支持的随机对照试验。研究团队将这些研究纳入动态社会网络框架,研究网络在 MOUD 治疗开始前、治疗期间和治疗后长期的作用。研究团队分析了三种来源的社会网络支持:伴侣关系、家庭和同伴网络的结果。
在筛选出的 5193 篇文章中,有 8 项研究符合纳入标准。五项研究表明,社会网络支持对改善 MOUD 治疗结果有统计学意义。我们发现家庭社会网络支持的积极影响得到了最强有力的支持。
社交网络显著影响阿片类药物使用障碍治疗的效果。虽然负面社会关系会加剧成瘾,但积极的社会支持网络可以放大药物治疗的益处。可以设计针对改善治疗结果的干预措施,并将其添加到 MOUD 治疗中,评估其对提高患者从阿片类药物使用障碍中康复的几率和扭转阿片类药物死亡人数上升趋势的影响。