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沙特阿拉伯利雅得无症状和轻度新冠病毒感染的临床表现

Clinical Presentation of Asymptomatic and Mild SARS-CoV-2 Infection in Riyadh, Saudi Arabia.

作者信息

Bin Abdulrahman Khalid A, Bamosa Abdullah O, Aseri Khaled S, Bukhari Abdullah I, Masuadi Emad M

机构信息

Department of Medical Education and Department of Internal Medicine, College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.

Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

J Multidiscip Healthc. 2021 Jun 8;14:1341-1347. doi: 10.2147/JMDH.S315718. eCollection 2021.

Abstract

BACKGROUND

There is substantial evidence that most SARS-CoV-2 infections are mild or even asymptomatic, yet they can transmit the virus to others. The current study described the clinical presentation of mild COVID-19 cases isolated in the ministry of health (MOH) quarantines in Riyadh, Saudi Arabia.

METHODS

A cross-sectional study targeted the SARS-CoV-2 PCR +ve asymptomatic and mild COVID-19 patients isolated in the Saudi MOH quarantines in Riyadh city between July and December 2020. The confirmed COVID-19 patients were enrolled and interviewed by telephones after obtaining the informed consent.

RESULTS

The study included 223 patients with a mean age of 32.5±10.7 years old. The majority were male 156 (70%). Only 27 [12.1%; 95% CI = (8.1-17.1%)] were asymptomatic. General fatigue was the most common reported symptom, 43.5%, followed by headache with 42.6%, and cough by 38.1%. Anosmia and ageusia were reported by 33.2% and 31.4%, respectively. The least common reported symptoms were vomiting, earache, and nausea with 1.8%, 4.0%, and 7.6%, respectively.

CONCLUSION

The top five clinical manifestations of mild COVID-19 cases were general fatigue, headache, cough, anosmia, and ageusia. Only 12% of confirmed COVID-19 cases were asymptomatic.

摘要

背景

有大量证据表明,大多数新冠病毒感染是轻症甚至无症状,但仍可将病毒传播给他人。本研究描述了在沙特阿拉伯利雅得卫生部隔离区隔离的轻症新冠肺炎病例的临床表现。

方法

一项横断面研究针对2020年7月至12月期间在利雅得市沙特卫生部隔离区隔离的新冠病毒核酸检测呈阳性的无症状和轻症新冠肺炎患者。在获得知情同意后,对确诊的新冠肺炎患者进行电话登记和访谈。

结果

该研究纳入了223名患者,平均年龄为32.5±10.7岁。大多数为男性,共156人(70%)。只有27人[12.1%;95%置信区间=(8.1-17.1%)]无症状。最常见的报告症状是全身乏力,占43.5%,其次是头痛,占42.6%,咳嗽占38.1%。嗅觉减退和味觉减退的报告率分别为33.2%和31.4%。最不常见的报告症状是呕吐、耳痛和恶心,分别占1.8%、4.0%和7.6%。

结论

轻症新冠肺炎病例的前五大临床表现是全身乏力、头痛、咳嗽、嗅觉减退和味觉减退。确诊的新冠肺炎病例中只有12%无症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638a/8197580/b238c639e0c5/JMDH-14-1341-g0001.jpg

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