Lambré Claude, Barat Baviera José Manuel, Bolognesi Claudia, Cocconcelli Pier Sandro, Crebelli Riccardo, Gott David Michael, Grob Konrad, Lampi Evgenia, Mengelers Marcel, Mortensen Alicja, Rivière Gilles, Steffensen Inger-Lise, Tlustos Christina, Van Loveren Henk, Vernis Laurence, Zorn Holger, Glandorf Boet, Herman Lieve, Kovalkovičová Natália, Liu Yi, Maia Joaquim, Chesson Andrew
EFSA J. 2021 Jun 10;19(6):e06633. doi: 10.2903/j.efsa.2021.6633. eCollection 2021 Jun.
The food enzyme containing chymosin (EC 3.4.23.4) and pepsin (EC 3.4.23.1) is derived from the abomasum of suckling lambs and goats by Caporal Enzymes, S.L. The food enzyme is intended to be used in milk processing for cheese production. As no concerns arise from the animal source of the food enzyme, from its manufacture, and based on the history of safe use and consumption, the Panel considered that toxicological data were not required and no exposure assessment was necessary. On the basis of literature data, the Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure could not be excluded, but the likelihood for this to occur was considered to be low. Based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
含凝乳酶（EC 3.4.23.4）和胃蛋白酶（EC 3.4.23.1）的食品酶由Caporal Enzymes, S.L.公司从哺乳羔羊和山羊的皱胃中提取。该食品酶旨在用于奶酪生产的牛奶加工过程。由于该食品酶的动物来源、生产过程均无安全问题，且基于其安全使用和消费历史，专家小组认为不需要毒理学数据，也无需进行暴露评估。根据文献数据，专家小组认为，在预期使用条件下，不能排除因膳食暴露引起过敏致敏和激发反应的风险，但认为发生这种情况的可能性较低。根据所提供的数据，专家小组得出结论，该食品酶在预期使用条件下不会引起安全问题。
