Guo Yuna, Wang Xiaoping, Bian Jingjing, Dou Zhi, Yang Liqiang, Ni Jiaxiang, Tang Yuanzhang
Pain Department, XuanWu Hospital, Capital Medical University, Beijing, China.
Wideochir Inne Tech Maloinwazyjne. 2021 Jun;16(2):362-368. doi: 10.5114/wiitm.2020.100739. Epub 2020 Nov 12.
Although the sphenopalatine ganglion (SPG) has been considered a site of therapeutic potential for cluster headache (CH), the optimal technique of SPG is still to be determined. Low-temperature plasma radiofrequency ablation (LTPRA) has been proposed as an alternative treatment for several neuropathic pain diseases.
To evaluate the effect of LTPRA of SPG in treating chronic and episodic CH.
The patients with CH, who achieved temporary pain relief following SPG block, treated using LTPRA between January 2015 and October 2017 were reviewed. Seventy-six patients were included: 50 patients suffered from episodic CH and the remaining 26 patients from chronic CH. The primary outcomes were clinical improvement rate, defined as the percentage of partial and complete pain relief results at 1 day, 12 months, and 24 months of follow-up after the operation.
Clinical improvement rates were 92.3%, 92.3% and 73.1% in chronic CH and 73.1%, 84% and 68% in episodic CH at each follow-up time point, respectively. 3 chronic CH patients and 7 episodic CH patients showed no pain relief after the operation. Drooping eyelids were found in 2 cases, one recovered at the 3-month follow-up but another one did not in the 24-month follow-up. No serious complications occurred intraoperatively or postoperatively.
LTPRA can be considered an effective and alternative surgical modality in treating patients with chronic and episodic CH, based on SPG block.
尽管蝶腭神经节(SPG)被认为是丛集性头痛(CH)潜在的治疗部位,但SPG的最佳治疗技术仍有待确定。低温等离子体射频消融术(LTPRA)已被提议作为几种神经性疼痛疾病的替代治疗方法。
评估SPG的LTPRA治疗慢性和发作性CH的效果。
回顾性分析2015年1月至2017年10月期间使用LTPRA治疗的CH患者,这些患者在SPG阻滞治疗后获得了暂时的疼痛缓解。纳入76例患者:50例为发作性CH患者,其余26例为慢性CH患者。主要结局指标为临床改善率,定义为术后1天、12个月和24个月随访时部分和完全疼痛缓解结果的百分比。
在每个随访时间点,慢性CH患者的临床改善率分别为92.3%、92.3%和73.1%,发作性CH患者的临床改善率分别为73.1%、84%和68%。3例慢性CH患者和7例发作性CH患者术后疼痛未缓解。发现2例上睑下垂,1例在3个月随访时恢复,但另1例在24个月随访时未恢复。术中及术后均未发生严重并发症。
基于SPG阻滞,LTPRA可被认为是治疗慢性和发作性CH患者的一种有效且可替代的手术方式。