伊朗北部野生大鼠（）中的血清阳性率。
Seroprevalence of in Wild Rats () in Northern Iran.
作者信息
Hosseini Seyed Abdollah, Abediankenari Saeid, Amouei Afsaneh, Sarvi Shahabeddin, Sharif Mehdi, Rezaei Fatemeh, Daryani Ahmad
机构信息
Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Mazandaran, Sari, Iran.
Department of Parasitology, School of Medicine, Mazandaran University of Medical Science, Mazandaran, Sari, Iran.
出版信息
Vet Med Int. 2021 May 27;2021:6655696. doi: 10.1155/2021/6655696. eCollection 2021.
Rodents are considered as reservoir hosts for various pathogens (such as ) and have been revealed to play an important role in the spread of several infectious diseases to humans and other animals. The aim of this investigation was to survey the prevalence of anti- IgG antibodies in wild rats in Northern Iran. One hundred rats were caught using rat traps set in different areas in Northern Iran (September 2017). The thoracic cavity of each rat was opened, and then the blood sample was collected from the heart. IgG anti- antibodies were detected using the modified agglutination test (MAT) with a cutoff value equal to 1 : 40. Overall, 56% of rats were infected by . Considering the sex of rats, 45% of male and 55% of female rats were seropositive, but the differences were not statistically significant. There was a significant difference between seropositivity and habitat types and age of rodents. Our findings have public health implications and confirm the high seroprevalence of infection in northern Iran. The study established that wild rats represent an important and persistent wildlife intermediate host reservoir for .
啮齿动物被认为是多种病原体的储存宿主（如 ），并且已被揭示在几种传染病向人类和其他动物的传播中起重要作用。本调查的目的是调查伊朗北部野生大鼠中抗 IgG 抗体的流行情况。2017 年 9 月，在伊朗北部不同地区设置鼠夹捕获了 100 只大鼠。打开每只大鼠的胸腔，然后从心脏采集血样。使用改良凝集试验（MAT）检测 IgG 抗 抗体，截断值等于 1∶40。总体而言，56% 的大鼠感染了 。考虑大鼠的性别，45% 的雄性和 55% 的雌性大鼠血清呈阳性，但差异无统计学意义。血清阳性率与栖息地类型和啮齿动物年龄之间存在显著差异。我们的研究结果具有公共卫生意义，并证实了伊朗北部 感染的高血清流行率。该研究确定野生大鼠是 的重要且持续的野生动物中间宿主储存库。
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