Yin Chuang-Cheng, He Yong, Zhou Dong-Hui, Yan Chao, He Xian-Hui, Wu Song-Ming, Zhou Yang, Yuan Zi-Guo, Lin Rui-Qing, Zhu X Q
College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
J Parasitol. 2010 Dec;96(6):1233-4. doi: 10.1645/GE-2610.1. Epub 2010 Aug 11.
Toxoplasma gondii is widely distributed in humans and other animals, including wild rats throughout the world, but little is known of the prevalence of T. gondii in rats in China. The seroprevalence of T. gondii in rats ( Rattus norvegicus and Rattus flavipectus ) was investigated in Guangzhou, southern China, between November 2009 and January 2010. In total, 217 rat serum samples were collected; antibodies to T. gondii were detected by the modified agglutination test (MAT), and 7 (3.2%) were found positive (titers ≥ 1:40). The seroprevalence was higher (3.4%) in R. norvegicus than in R. flavipectus (3.0%), but the difference was not statistically significant (P > 0.05). All 7 positive rats were female; no T. gondii antibodies were detected in males. This is the first extensive survey of T. gondii infection in rats in southern China, and the results have public health implications in this region.
弓形虫广泛分布于人类和其他动物中，包括世界各地的野生大鼠，但在中国大鼠中弓形虫的流行情况却知之甚少。2009年11月至2010年1月期间，在中国南方的广州对大鼠（褐家鼠和黄胸鼠）中弓形虫的血清流行率进行了调查。总共收集了217份大鼠血清样本；采用改良凝集试验（MAT）检测弓形虫抗体，发现7份（3.2%）呈阳性（滴度≥1:40）。褐家鼠的血清流行率（3.4%）高于黄胸鼠（3.0%），但差异无统计学意义（P>0.05）。所有7只阳性大鼠均为雌性；在雄性大鼠中未检测到弓形虫抗体。这是中国南方首次对大鼠弓形虫感染进行的广泛调查，其结果对该地区的公共卫生具有重要意义。
