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一名儿科患者化疗后出现危及生命的口腔黏膜炎。

Life-threatening oral mucositis following chemotherapy in a pediatric patient.

作者信息

Tsuboi Kaoru, Tsuboi Norihiko, Sakamoto Kenichi, Takebayashi Akira, Tomizawa Daisuke, Nishimura Nao, Nakagawa Satoshi

机构信息

Department of Critical Care Medicine National Center for Child Health and Development Tokyo Japan.

Children's Cancer Center National Center for Child Health and Development Tokyo Japan.

出版信息

Clin Case Rep. 2021 Jun 10;9(6):e04356. doi: 10.1002/ccr3.4356. eCollection 2021 Jun.

DOI:10.1002/ccr3.4356
PMID:34136255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8190677/
Abstract

Severe oral mucositis as a complication of chemotherapy may lead to airway obstruction and require prolonged intubation. As its course is consistent with the course of neutropenia, airway management strategies should be determined individually.

摘要

严重口腔黏膜炎作为化疗的并发症可能导致气道阻塞并需要长期插管。由于其病程与中性粒细胞减少症的病程一致,气道管理策略应个体化确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7656/8190677/3e550568f307/CCR3-9-e04356-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7656/8190677/24833a1e8bf2/CCR3-9-e04356-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7656/8190677/3e550568f307/CCR3-9-e04356-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7656/8190677/24833a1e8bf2/CCR3-9-e04356-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7656/8190677/3e550568f307/CCR3-9-e04356-g003.jpg

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Int J Environ Res Public Health. 2020 Apr 3;17(7):2464. doi: 10.3390/ijerph17072464.
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Severe Oral Mucositis in Pediatric Cancer Patients: Survival Analysis and Predictive Factors.儿童癌症患者严重口腔黏膜炎:生存分析和预测因素。
Int J Environ Res Public Health. 2020 Feb 14;17(4):1235. doi: 10.3390/ijerph17041235.
3
Surgical tracheostomy in children with malignancy receiving intensive chemotherapy: A case series and review of literature.
儿童恶性肿瘤接受强化化疗后行外科气管切开术:病例系列及文献复习。
Pediatr Blood Cancer. 2020 Apr;67(4):e28105. doi: 10.1002/pbc.28105. Epub 2019 Dec 26.
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Evidence-based guidelines for the use of tracheostomy in critically ill patients.危重症患者气管切开术应用的循证指南
J Crit Care. 2017 Apr;38:304-318. doi: 10.1016/j.jcrc.2016.10.009. Epub 2016 Oct 20.
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Mucosal barrier injury, fever and infection in neutropenic patients with cancer: introducing the paradigm febrile mucositis.癌症中性粒细胞减少症患者的黏膜屏障损伤、发热和感染:引入发热性黏膜炎范例。
Br J Haematol. 2014 Nov;167(4):441-52. doi: 10.1111/bjh.13113. Epub 2014 Sep 6.
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Leukemia. 2013 Dec;27(12):2413-6. doi: 10.1038/leu.2013.153. Epub 2013 May 16.
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