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早期发现高安病:在脉搏可触及的儿童中诊断“无脉症”

Catching Takayasu Early: Diagnosing the "Pulseless" Disease in a Child with Palpable Pulses.

作者信息

Rao A R Santosh, Jahagirdar Vinay, Rama Kaanthi

机构信息

Amrutha Children's Hospital, Shamshabad, Hyderabad 501218, India.

Gandhi Medical College and Hospital, Secunderabad 500003, India.

出版信息

Case Rep Pediatr. 2021 May 27;2021:8885944. doi: 10.1155/2021/8885944. eCollection 2021.

Abstract

Takayasu arteritis is a systemic vasculitis of large vessels that mainly involves the aorta and its branches. It normally presents in the third decade of life and is rarely seen in children. We report a case of childhood Takayasu arteritis, in a 12-year-old girl, who presented with abdominal pain and hypertension. Although all her peripheral pulses were palpable, there was a discrepancy between her upper and lower limbs' blood pressure. CT angiography revealed stenosis of the abdominal aorta, at the origin of the celiac artery and right renal artery. She was started on steroids and an antihypertensive, after which she attained remission. Five years down the line, the child has sustained remission, with no signs of disease progression. Early diagnosis of Takayasu and initiation of immunosuppression, before the onset of the classic "pulseless" phase, may contribute to improved long-term prognosis.

摘要

高安动脉炎是一种主要累及主动脉及其分支的大血管系统性血管炎。它通常在生命的第三个十年出现,在儿童中很少见。我们报告一例12岁女童患儿童高安动脉炎的病例,她表现为腹痛和高血压。尽管她所有的外周脉搏都可触及,但她上下肢的血压存在差异。CT血管造影显示腹主动脉在腹腔干动脉和右肾动脉起始处狭窄。她开始接受类固醇和抗高血压药物治疗,之后病情缓解。五年后,该患儿持续缓解,没有疾病进展的迹象。在典型的“无脉”期出现之前对高安动脉炎进行早期诊断并开始免疫抑制治疗,可能有助于改善长期预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cb4/8177979/881e1c155442/CRIPE2021-8885944.001.jpg

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