Azrieli Faculty of Medicine, Bar-Ilan University Safed, Safed, Israel.
Department of Otolaryngology Head and Neck Surgery, Galilee Medical Center, Nahariya, Israel.
Head Neck. 2021 Oct;43(10):3001-3009. doi: 10.1002/hed.26788. Epub 2021 Jun 16.
The aim of this study was to assess the survival outcomes of head and neck cancer (HNC) by socioeconomic status.
A national retrospective population-based cohort of HNC patients diagnosed in Israel between 2000 and 2017 was conducted. Site of residence and socioeconomic status were correlated with overall survival (OS), controlling for prognostic factors that included tumor site, stage, age, sex, and ethnic group.
Overall, 11 826 patients were identified. Patients from high socioeconomic areas had better overall 5-year survival than patients from low socioeconomic areas (p < 0.005). Patients in stage 3 from a high socioeconomic status had a longer median survival rate of 1.5 years than patients in the low-status group. In a cox proportional hazards analysis, we found age >65 (HR 2.91, 95% confidence interval [CI]: 2.75-3.09, p < 0.001) and low socioeconomic group (HR 1.25, 95% CI: 1.18-1.33, p < 0.001) to be correlated with inferior OS.
Our findings show that patients with HNC living in low socioeconomic areas had worse OS.
本研究旨在评估头颈部癌症（HNC）的生存结局与社会经济地位之间的关系。
本研究对 2000 年至 2017 年间在以色列被诊断为 HNC 的患者进行了全国性回顾性基于人群的队列研究。居住地和社会经济地位与总体生存率（OS）相关，同时控制了肿瘤部位、分期、年龄、性别和种族等预后因素。
共纳入 11826 例患者。来自高社会经济地区的患者的总体 5 年生存率优于来自低社会经济地区的患者（p<0.005）。处于 3 期且社会经济地位较高的患者的中位生存时间比社会经济地位较低的患者长 1.5 年。在 Cox 比例风险分析中，我们发现年龄>65 岁（HR 2.91，95%置信区间 [CI]：2.75-3.09，p<0.001）和低社会经济群体（HR 1.25，95% CI：1.18-1.33，p<0.001）与较差的 OS 相关。
我们的研究结果表明，居住在低社会经济地区的 HNC 患者的 OS 较差。
