Riley S M, Blackstone E H, Sterling W A, Diethelm A G
Surg Gynecol Obstet. 1978 Feb;146(2):203-8.
This noninvasive echocardiographic study of cardiac performance in 27 patients with chronic renal failure and vascular access documented the magnitude of forward cardiac output to be 65 per cent of the observed index. Hemodialysis resulted in acute hemodynamic changes, including an average fall in the cardiac index of 57 per cent, presumably because of a 40 per cent decrease in left ventricular filling volume. In patients in whom the vascular access had functioned longest, a time related cardiac decompensation is suggested by a cardiac index of significantly less than normal, p, 0.0013, with occlusion. Ventricular function was suboptimal three months post-transplant, as reflected by a continued low cardiac index and depressed ejection fraction, although the general reduction in cardiac index and diastolic volume on postoperative day 7 was of the magnitude expected from arteriovenous access occlusion.
这项针对27例慢性肾衰竭和血管通路患者心脏功能的无创超声心动图研究表明,心脏前向输出量为观察指标的65%。血液透析导致急性血流动力学变化,包括心脏指数平均下降57%,这可能是由于左心室充盈量减少40%所致。在血管通路使用时间最长的患者中,心脏指数显著低于正常水平(p < 0.0013),提示存在与时间相关的心脏失代偿。移植后三个月心室功能仍未达到最佳状态,表现为心脏指数持续偏低和射血分数降低,尽管术后第7天心脏指数和舒张容积的总体降低幅度与动静脉通路阻塞预期的幅度相当。