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探讨有和没有精神障碍的异质困扰癌症患者群体中癌症复发恐惧。

Exploring Fear of Cancer Recurrence in a Sample of Heterogeneous Distressed Cancer Patients with and Without a Psychiatric Disorder.

机构信息

Department of Psychiatry, Radboud University Medical Centre, 6525, EX, Nijmegen, The Netherlands.

Department of Psychiatry, Radboud University Medical Centre for Mindfulness, Reinier Postlaan, Postbus 9101, 6500, HB, Nijmegen, The Netherlands.

出版信息

J Clin Psychol Med Settings. 2021 Sep;28(3):419-426. doi: 10.1007/s10880-021-09776-2. Epub 2021 Jun 17.

Abstract

Fear of Cancer Recurrence (FCR) is a concern among cancer patients. Recent insights suggest that FCR should be viewed as a distinct syndrome. However, few studies have explored its overlap with psychiatric morbidity. We examined this overlap in a sample of distressed cancer patients. Self-referred patients (n = 245) were assessed with the Structured Clinical Interview for DSM-IV-TR Axis-I disorders and the Fear of Cancer Recurrence Inventory-Short Form. Proportions of patients with and without a psychiatric disorder meeting validated cut-offs for screening and clinically relevant FCR were compared. The prevalence of psychiatric disorders was 36%. Clinically relevant FCR was found in 198 patients (81%). Patients with a current psychiatric disorder reported clinically relevant FCR more frequently (89%) compared to those with no disorder (77%). Of patients reporting clinically relevant FCR, the majority (61%) did not additionally meet the criteria for a psychiatric disorder. These findings suggest that there should be particular attention for patients with elevated levels of FCR, warranting FCR-specific treatment.Trial registry number Clinicaltrials.gov NCT02138513.

摘要

癌症复发恐惧 (Fear of Cancer Recurrence, FCR) 是癌症患者关注的问题。最近的研究结果表明,FCR 应该被视为一种独特的综合征。然而,很少有研究探讨其与精神疾病发病率的重叠。我们在一组焦虑的癌症患者中研究了这种重叠。自我转诊的患者(n=245)接受了 DSM-IV-TR 轴 I 障碍的结构化临床访谈和癌症复发恐惧量表-短式的评估。比较了符合筛选和临床相关 FCR 验证标准的有和没有精神障碍的患者的比例。精神障碍的患病率为 36%。在 198 名患者中发现了临床相关的 FCR(81%)。与没有障碍的患者(77%)相比,目前患有精神障碍的患者更频繁地报告临床相关的 FCR(89%)。在报告临床相关 FCR 的患者中,大多数(61%)并未另外符合精神障碍的标准。这些发现表明,对于 FCR 水平升高的患者应特别关注,需要进行 FCR 特异性治疗。试验注册号:Clinicaltrials.gov NCT02138513。

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