Lazymova Z A, Asadullaev T A, Mamedov E Sh, Akhverdieva R Ia
Vopr Virusol. 1988 Mar-Apr;33(2):163-5.
Experimental studies of the influence of bis-(N,N'-uracil-1-yl)-selenoxomethane (I) and sodium selenite (II) on influenza virus reproduction on pieces of chorioallantoic membrane, both alone and in combination with remantadine and ribavirin, were carried out. The antiviral effects of both preparations were found to be enhanced in combination with effective and ineffective remantadine concentrations, whereas with ribavirin the additive effect was observed only in combination of the former preparation with ribavirin effective concentration. Combination of ribavirin with sodium selenite did not enhance the antiviral effect of the latter even when the effective concentration of nucleoside was used.
开展了双（N，N'-尿嘧啶-1-基）-亚硒基甲烷（I）和亚硒酸钠（II）对绒毛尿囊膜片上流感病毒繁殖的影响的实验研究，研究了它们单独使用以及与金刚烷胺和利巴韦林联合使用时的情况。发现两种制剂与有效和无效浓度的金刚烷胺联合使用时，其抗病毒效果均增强，而与利巴韦林联合使用时，仅在前一种制剂与利巴韦林有效浓度联合使用时观察到相加作用。即使使用核苷的有效浓度，利巴韦林与亚硒酸钠联合使用也不会增强后者的抗病毒效果。
