Ignat'ev G M, Gribencha S V, Vorob'eva M S, Barinskiĭ I F
Vopr Virusol. 1988 Mar-Apr;33(2):232-5.
Experimental data on the effectiveness of two schedules of vaccination against human acute encephalomyelitis, one conventional, using 12 injections, and another shortened, using 8 injections, are presented. The experiments in inbred mice evaluating the general resistance, virus-neutralizing antibody titres, resistance in adoptive transfer tests, and values of lymphocyte blastogenesis test showed no statistically significant differences between the shortened vaccination schedule and the conventional one. Experimentally, the shortened vaccination schedule is as effective as the conventional one.
本文展示了两种针对人类急性脑脊髓炎的疫苗接种方案有效性的实验数据，一种是传统方案，需注射12次，另一种是缩短方案，需注射8次。在近交系小鼠中进行的实验评估了一般抵抗力、病毒中和抗体滴度、过继转移试验中的抵抗力以及淋巴细胞增殖试验的值，结果显示缩短的疫苗接种方案与传统方案之间没有统计学上的显著差异。实验表明，缩短的疫苗接种方案与传统方案同样有效。
