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新冠疫情期间商用洗手液的使用:对抗菌药物耐药性的担忧

Commercial Hand Sanitizers use amid COVID-19 Pandemic: the Concerns of Antimicrobial Resistance.

作者信息

Assefa Desta, Melaku Tsegaye

机构信息

School of Pharmacy, Jimma University, Oromia, Ethiopia.

出版信息

Infect Drug Resist. 2021 Jun 10;14:2183-2185. doi: 10.2147/IDR.S317767. eCollection 2021.

DOI:10.2147/IDR.S317767
PMID:34140787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8204133/
Abstract

Following the outbreak of novel coronavirus disease, the rising concerns about the prevalence of alcohol-based hand sanitizers' inappropriate use and substandard products in the market create an ongoing safety concern. They can cause frequent exposure of microorganisms to below the alcohol concentrations to the range recommended for infection prevention and development of mutations. Thus, it is invaluable to sensitize the scientific community for further researches to provide additional evidence. Additionally, regulation of quality and proper use of alcohol-based hand sanitizers should be effectively promoted. This commentary justifies the impact of COVID-19 on the current and future use of alcohol-based hand sanitizers.

摘要

新型冠状病毒病爆发后,人们越来越担心市场上酒精类洗手液的不当使用和不合格产品的流行,这引发了持续的安全担忧。它们可能导致微生物频繁暴露于低于预防感染和突变发生所推荐浓度范围的酒精浓度环境中。因此,提高科学界对此的认识以进行进一步研究以提供更多证据非常重要。此外,应有效促进对酒精类洗手液质量和正确使用的监管。本评论阐述了COVID-19对当前和未来酒精类洗手液使用的影响。

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本文引用的文献

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Antimicrobial Resistance as a Hidden Menace Lurking Behind the COVID-19 Outbreak: The Global Impacts of Too Much Hygiene on AMR.抗菌药物耐药性:新冠疫情背后潜藏的隐性威胁——过度卫生对耐药性的全球影响
Front Microbiol. 2020 Dec 15;11:590683. doi: 10.3389/fmicb.2020.590683. eCollection 2020.
2
COVID-19 and frequent use of hand sanitizers; human health and environmental hazards by exposure pathways.COVID-19 与频繁使用手部消毒剂;通过暴露途径对人类健康和环境造成危害。
Sci Total Environ. 2020 Nov 10;742:140561. doi: 10.1016/j.scitotenv.2020.140561. Epub 2020 Jun 27.
3
Hand sanitisers amid CoViD-19: A critical review of alcohol-based products on the market and formulation approaches to respond to increasing demand.新冠疫情期间的手部消毒剂:对市场上基于酒精的产品和为满足日益增长的需求而采用的配方方法的批判性回顾。
Int J Pharm. 2020 Jun 30;584:119431. doi: 10.1016/j.ijpharm.2020.119431. Epub 2020 May 16.
4
The pandemic of COVID-19 and its implications for the purity and authenticity of alcohol-based hand sanitizers: The health risks associated with falsified sanitizers and recommendations for regulatory and public health bodies.COVID-19 大流行及其对酒精类手部消毒剂的纯度和真实性的影响:与假冒消毒剂相关的健康风险以及对监管和公共卫生机构的建议。
Res Social Adm Pharm. 2021 Jan;17(1):2050-2051. doi: 10.1016/j.sapharm.2020.04.014. Epub 2020 Apr 20.
5
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges.严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)和 2019 年冠状病毒病(COVID-19):疫情和挑战。
Int J Antimicrob Agents. 2020 Mar;55(3):105924. doi: 10.1016/j.ijantimicag.2020.105924. Epub 2020 Feb 17.
6
Increasing tolerance of hospital to handwash alcohols.提高医院对手洗酒精的耐受性。
Sci Transl Med. 2018 Aug 1;10(452). doi: 10.1126/scitranslmed.aar6115.
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Evolution of high-level resistance during low-level antibiotic exposure.低水平抗生素暴露下高水平耐药性的演变。
Nat Commun. 2018 Apr 23;9(1):1599. doi: 10.1038/s41467-018-04059-1.