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经食管起搏在儿童及青少年心悸评估中的作用

Role of transesophageal pacing in evaluation of palpitations in children and adolescents.

作者信息

Pongiglione G, Saul J P, Dunnigan A, Strasburger J F, Benson D W

机构信息

Children's Memorial Hospital, Chicago, Illinois 60614.

出版信息

Am J Cardiol. 1988 Sep 15;62(9):566-70. doi: 10.1016/0002-9149(88)90656-x.

DOI:10.1016/0002-9149(88)90656-x
PMID:3414549
Abstract

Transesophageal atrial pacing was used to evaluate the cause of palpitations in 28 patients ages 3 to 18 years (mean 11). Palpitations were defined as the sustained (seconds to minutes) sensation of rapid heart beating. Each patient had had greater than 2 episodes of palpitations. No patient had other evidence of heart disease. Standard electrocardiogram was normal (23 of 28 patients), demonstrated ventricular preexcitation (3 of 28 patients) or demonstrated short PR interval (2 of 28 patients). In selected patients, ambulatory monitoring (11 patients) or exercise testing (3 patients) was performed but failed to demonstrate a cause of palpitations. In an effort to initiate tachycardia, a similar transesophageal atrial pacing protocol was performed in each patient. The protocol consisted of: (1) single extrastimuli at progressively closer intervals during sinus rhythm and after an 8-beat pacing train at greater than or equal to 1 cycle lengths and (2) incremental atrial pacing to the point of second-degree atrioventricular block. If this pacing regimen failed to initiate tachycardia, it was repeated during isoproterenol infusion (0.02, 0.05 and 0.1 micrograms/kg/min) and then following intravenous atropine (0.04 mg/kg) administration. During the study, tachycardia was initiated in 20 of 28 patients (71%) (14 of 15 patients greater than 10 years, 6 of 13 patients less than or equal to 10 years; p less than 0.01, Fisher's exact test). Electrophysiologic characteristics of induced tachycardia suggested reentry within the atrioventricular node (8 of 20 patients) or orthodromic reciprocating tachycardia (12 of 20 patients). In 3 of 12 patients with orthodromic reciprocating tachycardia, a transition to atrial fibrillation was observed.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

经食管心房起搏用于评估28例年龄在3至18岁(平均11岁)的心悸患者的病因。心悸被定义为持续(数秒至数分钟)的心跳加速感觉。每位患者有超过2次心悸发作。无患者有其他心脏病证据。标准心电图正常(28例患者中的23例),显示心室预激(28例患者中的3例)或显示PR间期缩短(28例患者中的2例)。部分患者进行了动态监测(11例患者)或运动试验(3例患者),但未能找出心悸原因。为诱发心动过速,对每位患者执行了类似的经食管心房起搏方案。该方案包括:(1)在窦性心律期间以及在大于或等于1个心动周期长度的8次起搏序列后,以逐渐缩短的间隔发放单个期外刺激;(2)递增性心房起搏直至二度房室传导阻滞。如果该起搏方案未能诱发心动过速,则在输注异丙肾上腺素(0.02、0.05和0.1微克/千克/分钟)期间重复进行,然后在静脉注射阿托品(0.04毫克/千克)后重复进行。研究期间,28例患者中的20例(71%)诱发了心动过速(15例年龄大于10岁的患者中的14例,13例年龄小于或等于10岁的患者中的6例;P<0.01,Fisher精确检验)。诱发心动过速的电生理特征提示房室结内折返(20例患者中的8例)或顺向型房室折返性心动过速(20例患者中的12例)。在12例顺向型房室折返性心动过速患者中的3例中,观察到转变为心房颤动。(摘要截短于250字)

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