Barkin J S, Reiner D K, Goldberg R I, Phillips R S
University of Miami, School of Medicine, Miami Beach, Florida.
Am J Gastroenterol. 1988 Sep;83(9):930-4.
The purpose of this prospective study was to evaluate the effect of compliance versus noncompliance with a behavior modification program (BMP) for 35 patients who underwent implantation of 51 Garren-Edwards gastric bubbles (GEGB). Criteria for morbid obesity was met by every patient. Two patient groups were formed by self-selection. Compliant patients (group I) attended 75% or more of the BMP. Group II consisted of noncompliant patients, and was divided further into partially complaint and totally noncompliant. A significant difference was found in both loss of weight and loss of body mass index (BMI) between the complaint and noncompliant groups, with no significant difference in weight loss between the partially and totally noncompliant groups. Patients' compliant or noncompliant behavior had a significant effect on changes in weight (p = 0.007) and body mass index (p = 0.005). Sixteen patients had two consecutive bubble implants. The rate of compliance was significantly higher during the first implant program, with a significantly greater loss in both weight and BMI for compliant patients. Follow-up data for 28 of 35 patients revealed a continued, albeit small, average weight decrease. In summary, weight loss does not result from the gastric bubble alone. Our study demonstrates that the key factor is compliance with a behavior modification program.
这项前瞻性研究的目的是评估35例接受51个加伦-爱德华兹胃泡（GEGB）植入术的患者遵守或不遵守行为矫正计划（BMP）的效果。所有患者均符合病态肥胖标准。通过自我选择形成了两个患者组。依从性好的患者（第一组）参加了75%或更多的行为矫正计划。第二组由不依从的患者组成，进一步分为部分依从和完全不依从。依从组和不依从组在体重减轻和体重指数（BMI）降低方面均存在显著差异，部分不依从组和完全不依从组在体重减轻方面无显著差异。患者的依从或不依从行为对体重变化（p = 0.007）和体重指数变化（p = 0.005）有显著影响。16例患者连续进行了两次胃泡植入。在第一次植入计划期间，依从率显著更高，依从性好的患者在体重和BMI方面的下降幅度显著更大。35例患者中的28例的随访数据显示，体重持续下降，尽管幅度较小。总之，体重减轻并非仅由胃泡导致。我们的研究表明，关键因素是遵守行为矫正计划。
