Graduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil.
Graduate Program in Medical Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil.
Clin Nutr. 2021 Jul;40(7):4807-4819. doi: 10.1016/j.clnu.2021.03.005. Epub 2021 Mar 10.
Garlic, a member of the Allium family, widely used in cooking for many centuries, displays well described antioxidant and anti-inflammatory properties, as a result of its constituent organosulfur compounds, such as alliin, allicin, ajoene S-allyl-cysteine, diallyl sulfide and diallyl disulfide, among others. Although garlic has demonstrated beneficial effects in cardiovascular disease, diabetes, and cancer, its efficacy as a therapeutic intervention in chronic kidney disease remains to be proven. This review thus focuses on the potential benefits of garlic as a treatment option in chronic kidney disease. and its ability to mitigate associated cardiovascular complications and gut dysbiosis.
大蒜，葱属植物的一员，在烹饪中被广泛使用了数个世纪，因其所含的有机硫化合物而具有良好描述的抗氧化和抗炎特性，这些化合物包括蒜氨酸、蒜素、葱烯、S-烯丙基半胱氨酸、二烯丙基硫醚和二烯丙基二硫醚等。尽管大蒜已被证明在心血管疾病、糖尿病和癌症方面具有有益的效果，但它作为慢性肾脏病治疗干预的疗效仍有待证明。因此，本综述重点关注大蒜作为慢性肾脏病治疗选择的潜在益处，以及它减轻相关心血管并发症和肠道菌群失调的能力。
