Melguizo-Rodríguez Lucía, García-Recio Enrique, Ruiz Concepción, De Luna-Bertos Elvira, Illescas-Montes Rebeca, Costela-Ruiz Víctor J
Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, Avda. Ilustración 60, 18016, Granada, Spain.
Institute of Biosanitary Research, Ibs.Granada, C/Doctor Azpitarte 4, 4a Planta, 18012, Granada, Spain.
Food Funct. 2022 Mar 7;13(5):2415-2426. doi: 10.1039/d1fo03180e.
Garlic is one of the most widely employed condiments in cooking. It has also been used since ancient times in traditional plant-based medicine, largely based on its organosulfur compounds. The objective of this study was to provide updated information on the biological and therapeutic garlic properties. Garlic has been found to possess important biological properties with high therapeutic potential, which is influenced by the mode of its utilization, preparation, and extraction. It has been attributed with antioxidant, anti-inflammatory, and immunomodulatory capacities. Garlic, in particular its organosulfur compounds, can maintain immune system homeostasis through positive effects on immune cells, especially by regulating cytokine proliferation and expression. This may underlie their usefulness in the treatment of infectious and tumor processes. These compounds can also offer vascular benefits by regulating lipid metabolism or by exerting antihypertensive and antiaggregant effects. However, further clinical trials are warranted to confirm the therapeutic potential of garlic and its derivatives.
大蒜是烹饪中使用最广泛的调味品之一。自古以来，它也被用于传统植物医学，主要是基于其有机硫化合物。本研究的目的是提供有关大蒜生物学和治疗特性的最新信息。已发现大蒜具有重要的生物学特性和较高的治疗潜力，这受到其使用方式、制备方法和提取方式的影响。它具有抗氧化、抗炎和免疫调节能力。大蒜，尤其是其有机硫化合物，可以通过对免疫细胞产生积极影响来维持免疫系统的稳态，特别是通过调节细胞因子的增殖和表达。这可能是它们在治疗感染性疾病和肿瘤过程中发挥作用的基础。这些化合物还可以通过调节脂质代谢或发挥抗高血压和抗聚集作用来对血管有益。然而，需要进一步的临床试验来证实大蒜及其衍生物的治疗潜力。
