Wyckoff Jennifer A, Brown Florence M
University of Michigan, Ann Arbor, MI.
Joslin Diabetes Center, Boston, MA.
Diabetes Spectr. 2021 May;34(2):119-132. doi: 10.2337/ds20-0103. Epub 2021 May 25.
Continuous glucose monitoring (CGM) is being used with increasing frequency as an adjunct to self-monitoring of blood glucose in pregnancy, and novel targets based on CGM data are becoming standardized. This adoption of CGM is the result of its improving accuracy, patient preference, and evolving data demonstrating associations of novel targets such as time in range (TIR) with pregnancy and neonatal outcomes. A greater understanding of the relationship of various CGM metrics to outcomes in pregnancy complicated by diabetes is needed. It is clear that TIR parameters need to be uniquely lower for pregnant women than for nonpregnant individuals. CGM technology is also an integral part of hybrid closed-loop insulin delivery systems. These insulin delivery systems will be a significant advance in the management of diabetes during pregnancy if they can achieve the pre- and postprandial targets required for pregnancy and optimize TIR.
持续葡萄糖监测（CGM）作为孕期自我血糖监测的辅助手段，其使用频率日益增加，基于CGM数据的新指标正趋于标准化。CGM的这种应用是因其准确性提高、患者偏好以及不断发展的数据表明诸如血糖达标时间（TIR）等新指标与妊娠及新生儿结局之间存在关联。我们需要更深入了解各种CGM指标与糖尿病合并妊娠结局之间的关系。显然，孕妇的TIR参数需要比非孕妇更低。CGM技术也是混合闭环胰岛素输注系统的一个组成部分。如果这些胰岛素输注系统能够实现孕期所需的餐前和餐后目标并优化TIR，那么它们将成为孕期糖尿病管理的一项重大进展。
