Jones Jesse, Bolding Mark, Ullman Henrik, Kaneko Naoki, Tateshima Satoshi
Departments of Neurosurgery and Radiology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Department of Radiology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Front Neurol. 2021 Jun 3;12:671380. doi: 10.3389/fneur.2021.671380. eCollection 2021.
Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Due to its non-invasive yet immediate ablative effects, focused ultrasound may allow safer treatment of AVMs. However, further studies are needed to clarify its efficacy and side effect profile.
脑动静脉畸形（AVM）虽罕见但严重，在各种治疗方式的风险与观察期间不确定的自然病程之间，常常带来治疗上的两难困境。我们描述了关于使用聚焦超声作为一种新型治疗策略的初步数据。在一个AVM模型中，单次超声治疗可逐渐减少通过病变的血流量，且不会引发破裂。由于其具有非侵入性但即时的消融作用，聚焦超声可能使AVM的治疗更安全。然而，还需要进一步研究来阐明其疗效和副作用情况。
