金黄色葡萄球菌中具有赋予洗必泰和依沙吖啶抗性能力的抗微生物和抗生素抗性质粒。
Antiseptic and antibiotic resistance plasmid in Staphylococcus aureus that possesses ability to confer chlorhexidine and acrinol resistance.
作者信息
Yamamoto T, Tamura Y, Yokota T
机构信息
Department of Bacteriology, School of Medicine, Juntendo University, Tokyo, Japan.
出版信息
Antimicrob Agents Chemother. 1988 Jun;32(6):932-5. doi: 10.1128/AAC.32.6.932.
Abstract
Plasmid pSAJ1 from a methicillin- and gentamicin-resistant strain of Staphylococcus aureus had am molecular size of 50 kilobases and conferred resistance not only to kanamycin, gentamicin, tobramycin, amikacin, benzalkonium chloride, acriflavin, and ethidium bromide but also to chlorhexidine. In addition, the cloned antiseptic resistance gene(s) manifested acrinol resistance in Escherichia coli.
摘要
来自一株耐甲氧西林和庆大霉素的金黄色葡萄球菌的质粒pSAJ1，分子大小为50千碱基，它不仅赋予对卡那霉素、庆大霉素、妥布霉素、阿米卡星、苯扎氯铵、吖啶黄素和溴化乙锭的抗性，还赋予对氯己定的抗性。此外，克隆的抗菌剂抗性基因在大肠杆菌中表现出对吖啶黄的抗性。
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