用于在活细胞和组织中成像酪氨酸酶活性的高选择性双光子荧光开启探针。
Highly selective two-photon fluorescent off-on probes for imaging tyrosinase activity in living cells and tissues.
机构信息
Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 120-750, Korea.
Department of Chemistry and Department of Energy Systems Research, Ajou University, Suwon, 443-749, Korea.
出版信息
Chem Commun (Camb). 2021 Jul 13;57(56):6911-6914. doi: 10.1039/d1cc02374h.
PMID:34152336
Abstract
A coumarin-based two-photon (TP) fluorescent off-on probe has been developed for detecting tyrosinase activity. High selectivity, sensitivity and biocompatibility enable the probes to successfully image tyrosinase activity in live cells and tissues using TP microscopy.
摘要
基于香豆素的双光子（TP）荧光开启型探针已被开发用于检测酪氨酸酶活性。高选择性、灵敏度和生物相容性使探针能够成功地使用 TP 显微镜在活细胞和组织中成像酪氨酸酶活性。
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