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女性尿道重建的最新进展。

Update on female urethral reconstruction.

机构信息

Urology Service, Hospital del Trabajador.

Department of Urology, Finis Terrae University, Santiago, Chile.

出版信息

Curr Opin Urol. 2021 Sep 1;31(5):486-492. doi: 10.1097/MOU.0000000000000907.

Abstract

PURPOSE OF REVIEW

Female urethral stricture (FUS) is not frequent but can be the cause of significant morbidity. A somewhat overlooked condition for years, it has received significant attention in recent times. In this review, we update the current evidence surrounding FUS management.

RECENT FINDINGS

It is estimated that FUS is present in about 1% of all women having check-ups for lower urinary tract symptoms. Etiology is considered as idiopathic in half of the cases, iatrogenic in one-third, whereas infection/inflammation and trauma account for the rest. Symptoms presented are usually nonspecific and nondiagnostic. Pelvic examination, uroflowmetry, endoscopy, and urethrography are the most frequently employed diagnostic tools. Urodynamics/video-urodynamics can be used to document obstruction and to differentiate true anatomic strictures from functional disorders. Urethral dilation (UD) is the most frequent management procedure, sometimes followed by self-dilation, but recurrence is high, at over 50%. By contrast, reconstructive surgery is far more efficient, with overall curative rates of around 90%.

SUMMARY

A high index of suspicion is required to identify FUS patients. UD is advised as a first approach but after one or two failed attempts, reconstruction at a referral center should be considered.

摘要

目的综述

女性尿道狭窄(FUS)并不常见,但可导致严重的发病率。多年来,它一直是一个被忽视的疾病,但近年来受到了广泛关注。在这篇综述中,我们更新了当前关于 FUS 管理的证据。

最近的发现

据估计,在所有因下尿路症状就诊的女性中,FUS 约占 1%。病因一半被认为是特发性的,三分之一是医源性的,而感染/炎症和创伤占其余部分。症状通常是非特异性和非诊断性的。盆腔检查、尿流率、内窥镜检查和尿道造影是最常使用的诊断工具。尿动力学/视频尿动力学可用于记录梗阻,并区分真性解剖狭窄与功能性障碍。尿道扩张(UD)是最常见的治疗方法,有时会进行自我扩张,但复发率很高,超过 50%。相比之下,重建手术的效果要好得多,总体治愈率约为 90%。

总结

需要高度怀疑 FUS 患者。建议首先进行 UD,但如果尝试一到两次后失败,应考虑在转诊中心进行重建。

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