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女性尿道成形术:当代思考。

Female urethroplasty: contemporary thinking.

机构信息

Eastern Health, Box Hill, VIC, Australia.

Auckland Hospital, Auckland, New Zealand.

出版信息

World J Urol. 2019 Apr;37(4):619-629. doi: 10.1007/s00345-018-2564-4. Epub 2018 Nov 19.

Abstract

PURPOSE

Female urethral stricture disease is a rare entity. To date, its diagnosis and treatment have been poorly studied, with small numbers, and variable definitions of success. With growing interest in this area of reconstructive urology, there is an increased number of surgical techniques. In this article, we review current trends, definitions, etiologies and surgical techniques available for management of FUSD.

METHOD

We completed a review of publications in: English; Pubmed, and Google scholar. Key words identified for review were, female urethra stricture, female urethroplasty and female urethral dilation, female pelvic fracture, and female urethral reconstruction. Papers were reviewed, and references of relevant papers reviewed.

RESULTS

Iatrogenic injury is the most common cause of female urethral stricture disease. Assessment requires a thorough patient history, examination and either flexible cystoscopy and/or fluoroscopic urodynamics to determine the most appropriate surgical approach for stricture repair. Multiple open urethroplasty techniques are described with various grafts and flaps, with good medium-term success. Minimally invasive techniques remain well-employed but have poor long-term success, with increased failure with multiple attempts at treatment.

CONCLUSION

Female urethral stricture disease is a complex clinical entity that requires a measured and thorough evaluation. Individualized approach should be undertaken reviewing the patient's symptoms, the stricture's etiology, surrounding vaginal tissue health and stricture location. Promising medium-term success rates with vaginal flaps and buccal mucosal graft urethroplasty have been reported, with disappointing long-term results from repeated urethral dilation. Further research comparing techniques and defining successful long-term outcomes is required.

摘要

目的

女性尿道狭窄疾病较为罕见。迄今为止,其诊断和治疗研究甚少,相关病例数量较少,成功定义也存在差异。由于人们对重建泌尿外科这一领域的兴趣日益浓厚,手术技术也在不断增加。本文我们回顾了目前女性尿道狭窄的治疗趋势、定义、病因学和手术技术。

方法

我们检索了英文文献,包括 Pubmed 和 Google Scholar,检索词包括女性尿道狭窄、女性尿道成形术和女性尿道扩张、女性骨盆骨折和女性尿道重建。我们对这些文献进行了评估,并对相关文献的参考文献进行了回顾。

结果

医源性损伤是女性尿道狭窄最常见的病因。评估需要对患者的病史、检查进行全面了解,并通过软性膀胱镜检查和/或放射性尿动力学检查来确定最合适的狭窄修复手术方法。目前已有多种开放式尿道成形术技术,使用了各种移植物和皮瓣,具有良好的中期成功率。微创技术仍广泛应用,但长期成功率较差,随着治疗次数的增加,失败率也会增加。

结论

女性尿道狭窄疾病是一种复杂的临床实体,需要进行全面的评估。应该根据患者的症状、狭窄的病因、周围阴道组织健康状况和狭窄部位来制定个体化的治疗方案。阴道皮瓣和颊黏膜移植尿道成形术的中期成功率较高,但重复尿道扩张的长期效果令人失望。需要进一步研究比较不同技术,并确定成功的长期结果。

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