Urology Service, Hospital del Trabajador, Ramón Carnicer 185, Santiago, Chile.
School of Medicine, Andres Bello University, Santiago, Chile.
World J Urol. 2020 Dec;38(12):3047-3054. doi: 10.1007/s00345-019-02958-6. Epub 2019 Sep 21.
Female urethral stricture (FUS) is an infrequent entity, but may cause significant morbidity. Despite a rising interest in recent years, there is still scarce published information. In this article, we review FUS with a special attention to the use of dorsal buccal mucosa grafts (DBMG).
A literature search was conducted summarizing information about etiology, anatomy, diagnosis, and management. A detailed description of our technique for DBMG urethroplasty is given, with a summary report of our experience and results.
FUS accounts for about 1% of all women consulting for lower urinary tract symptoms (LUTS). Diagnosis is suspected in front of persistent LUTS suggestive of obstruction. Confirmatory tests are uroflowmetry, endoscopy, and urethrography; true anatomic strictures must be differentiated from functional or physiological obstructions. Initial management may include dilations, but recurrence is frequent. On the contrary, reconstructive surgery is highly efficient, with overall curative rates around 90%. For reconstruction, DBMG has gained popularity, because it would maintain intact the ventro-lateral urethral supporting structures, important for continence. The pathology of female strictures is unknown and neither the pre nor the intraoperative assessment allows determining the precise location and extent or the urethral damage; therefore, we advise extensive grafting of the entire urethra. Collected success of DBMG is 86% at a mean follow-up of 21 months. Morbidity is very low and de novo stress incontinence has not been reported.
Because of its many advantages, DMBG currently represents a prime choice for FUS reconstruction.
女性尿道狭窄(FUS)是一种罕见的疾病,但可能导致严重的发病率。尽管近年来人们对此越来越感兴趣,但发表的相关信息仍然很少。在本文中,我们特别关注颊黏膜后尿道成形术(DBMG)来回顾 FUS。
我们进行了文献检索,总结了病因、解剖、诊断和治疗方面的信息。详细描述了我们的 DBMG 尿道成形术技术,并总结了我们的经验和结果。
FUS 约占所有因下尿路症状(LUTS)就诊的女性的 1%。在出现持续的提示梗阻的 LUTS 时,怀疑存在 FUS。确认性测试包括尿流率、内窥镜检查和尿道造影术;必须将真正的解剖狭窄与功能性或生理性梗阻区分开来。初始治疗可能包括扩张,但复发很常见。相反,重建手术的效果非常高,总治愈率约为 90%。对于重建,DBMG 已广受欢迎,因为它可以保持尿道外侧的支持结构完整,这对控尿很重要。女性狭窄的病理机制尚不清楚,术前和术中评估都无法确定确切的位置和范围或尿道损伤;因此,我们建议对整个尿道进行广泛的移植物移植。在 21 个月的平均随访中,DBMG 的总成功率为 86%。发病率非常低,并且没有新发生的压力性尿失禁。
由于其诸多优点,DBMG 目前是 FUS 重建的首选。