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经两年干咳后偶然诊断出的胸腺黏液表皮样癌。

Mucoepidermoid carcinoma of the thymus incidentally diagnosed following two-years of non-productive cough.

作者信息

Thibodeau Ryan, Jafroodifar Abtin, Coelho Marlon, Kaminski Benjamin, Gitto Lorenzo, Zaccarini Daniel J, Scalzetti Ernest

机构信息

Department of Radiology, SUNY Upstate Medical University, Syracuse, NY.

Department of Pathology, SUNY Upstate Medical University, Syracuse, NY.

出版信息

Radiol Case Rep. 2021 Jun 11;16(8):2158-2163. doi: 10.1016/j.radcr.2021.05.006. eCollection 2021 Aug.

DOI:10.1016/j.radcr.2021.05.006
PMID:34158908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8202185/
Abstract

Mucoepidermoid carcinoma of the thymus is a rare primary thymic carcinoma. Radiologic imaging of this malignancy is rarely reported in literature. We present a patient who complained of a chronic cough for two years who was later found to have mucoepidermoid carcinoma of the thymus. Chest radiograph revealed a large anterior mediastinal mass. Follow-up computed tomography of the thorax demonstrated a large, heterogeneous anterior mediastinal mass with traversing vessels. F-18 fluorodeoxyglucose positron emission tomography-computed tomography demonstrated high avidity in the lesion with areas of diminished activity thought to represent necrosis. Following surgical resection, pathology revealed high-grade mucoepidermoid carcinoma of the thymus extending into the skeletal muscle and pericardium with evidence of lymphovascular invasion. The patient received external beam radiation therapy and has remained disease-free for three years.

摘要

胸腺黏液表皮样癌是一种罕见的原发性胸腺癌。关于这种恶性肿瘤的放射影像学在文献中鲜有报道。我们报告一例患者,该患者主诉慢性咳嗽两年,后来被发现患有胸腺黏液表皮样癌。胸部X线片显示前纵隔有一个大肿块。胸部后续计算机断层扫描显示前纵隔有一个大的、不均匀的肿块,有血管穿过。F-18氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描显示病变部位摄取高,活性降低区域被认为代表坏死。手术切除后,病理显示为高级别胸腺黏液表皮样癌,已延伸至骨骼肌和心包,并有淋巴血管侵犯的证据。该患者接受了外照射放疗,至今已无病生存三年。

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Multiphase contrast-enhanced computed tomography imaging features of salivary duct carcinoma: differentiation from other salivary gland malignancies.多相增强 CT 成像在涎腺癌诊断中的应用:与其他涎腺恶性肿瘤的鉴别诊断。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Nov;128(5):543-551. doi: 10.1016/j.oooo.2019.05.011. Epub 2019 Jun 6.
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Non-contrast computed tomography and magnetic resonance imaging features of mucoepidermoid carcinoma in the salivary glands.
唾液腺黏液表皮样癌的非增强计算机断层扫描和磁共振成像特征。
Oral Radiol. 2018 Jan;34(1):24-30. doi: 10.1007/s11282-017-0281-0. Epub 2017 Mar 27.
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State-of-the-Art Imaging of Salivary Gland Tumors.唾液腺肿瘤的最新成像技术
Neuroimaging Clin N Am. 2018 May;28(2):303-317. doi: 10.1016/j.nic.2018.01.009.
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Sci Rep. 2017 Mar 6;7:43907. doi: 10.1038/srep43907.
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Salivary gland tumours in a northern Chinese population: a 50-year retrospective study of 7190 cases.中国北方人群唾液腺肿瘤:一项对7190例病例的50年回顾性研究。
Int J Oral Maxillofac Surg. 2017 Mar;46(3):343-349. doi: 10.1016/j.ijom.2016.09.021. Epub 2016 Oct 19.
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