Abdelmasih Randa, Abdelmaseih Ramy, Reed Justin
Internal Medicine, University of Central Florida College of Medicine, Ocala, USA.
Cureus. 2021 May 19;13(5):e15117. doi: 10.7759/cureus.15117.
Statins are a class of medications indicated for atherosclerotic cardiovascular diseases and dyslipidemia. Ever since their introduction, various side effects have been reported with their use. Statin-induced myopathy is a well-established side effect of the medication, ranging in severity from mild myotoxicity to fatal rhabdomyolysis, with or without an increase in creatine kinase levels. Statin-induced diplopia, ptosis, or ophthalmoplegia are very rare, but they have been reported as adverse events in a handful of cases. These adverse events typically result from the progressive weakening of the external ocular musculature or the levator palpebrae superioris muscle. In this report, we present a rare case of statin-induced diplopia in a patient who had been on atorvastatin therapy for years. We believe this report will increase awareness among physicians about such an adverse event related to statins.
他汀类药物是一类用于治疗动脉粥样硬化性心血管疾病和血脂异常的药物。自引入以来，使用它们时已报告了各种副作用。他汀类药物引起的肌病是该药物公认的副作用，严重程度从轻度肌毒性到致命性横纹肌溶解不等，肌酸激酶水平可升高或不升高。他汀类药物引起的复视、上睑下垂或眼肌麻痹非常罕见，但在少数病例中已报告为不良事件。这些不良事件通常是由于眼外肌或提上睑肌逐渐减弱所致。在本报告中，我们介绍了一名长期服用阿托伐他汀治疗的患者发生他汀类药物引起的复视的罕见病例。我们相信本报告将提高医生对与他汀类药物相关的此类不良事件的认识。
