Kesten S, Hyland R H, Pruzanski W R, Kortan P P
Division of Respirology and Critical Care Medicine, Wellesley Hospital, Toronto, Ontario, Canada.
Drug Intell Clin Pharm. 1988 Jul-Aug;22(7-8):568-9. doi: 10.1177/106002808802200709.
A 23-year-old woman with asthma developed severe heartburn while using beclomethasone dipropionate. Esophageal candidiasis was diagnosed on endoscopy and confirmed by biopsy. Subsequent studies revealed mild hypogammaglobulinemia and mild impairment of neutrophil candidacidal activity, the significance of which is unknown. Esophageal candidiasis associated with the use of inhaled beclomethasone has not been previously reported.
一名23岁的哮喘女性在使用二丙酸倍氯米松时出现了严重的胃灼热。经内镜检查诊断为食管念珠菌病,并经活检证实。随后的研究显示有轻度低丙种球蛋白血症和中性粒细胞杀念珠菌活性轻度受损,其意义尚不清楚。此前尚未有吸入性二丙酸倍氯米松相关的食管念珠菌病的报道。