二丙酸倍氯米松与口咽念珠菌病
Beclomethasone dipropionate and oropharyngeal candidiasis.
作者信息
Milne L J, Crompton G K
出版信息
Br Med J. 1974 Sep 28;3(5934):797-8. doi: 10.1136/bmj.3.5934.797.
Abstract
A survey of 936 patients attending a respiratory diseases unit outpatient department was performed to assess the incidence of oropharyngeal candidiasis in patients inhaling beclomethasone dipropionate in daily doses of 400 mug or less. Throat swabs from 209 (41%) patients treated with beclomethasone were positive on culture for yeasts compared with positive swabs from 77 (27.2%) patients not receiving corticosteroid therapy either orally or by inhalation. Clinical oropharyngeal thrush, confirmed by culture, was detected in 28 (5.5%) patients inhaling beclomethasone, one (0.7%) patient receiving treatment with oral prednisolone, and two (0.7%) patients not being treated with corticosteroids.
摘要
对936名呼吸疾病科门诊患者进行了一项调查，以评估每日吸入丙酸倍氯米松剂量为400微克或更低的患者中口咽念珠菌病的发病率。接受丙酸倍氯米松治疗的209名（41%）患者的咽拭子培养出酵母呈阳性，相比之下，未接受口服或吸入皮质类固醇治疗的77名（27.2%）患者的咽拭子培养也呈阳性。经培养确诊的临床口咽念珠菌病在28名（5.5%）吸入丙酸倍氯米松的患者、1名（0.7%）接受口服泼尼松龙治疗的患者和2名（0.7%）未接受皮质类固醇治疗的患者中被检测到。
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