Fernandes Ramos Mariana, Boston David, Kinney Chad A, Coblinski João A, de Oliveira Camargo Flávio A
PhD, Soil Science Graduate Program, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Lead Scientist at New Iridium LLC, Boulder, CO, USA.
Sci Justice. 2021 Jul;61(4):401-409. doi: 10.1016/j.scijus.2021.03.002. Epub 2021 Mar 13.
Marijuana, dried and ground Cannabis, is the most consumed illicit drug in the world. Many undesirable and risky effects to human health are caused by its use. The medicinal use or legal recreational use of Cannabis has also been rising in many countries. These facts make traceability methodologies increasingly important whether for forensic use, such as drug trafficking eradication, or for quality control purposes of legal medicinal Cannabis. Consequently, the objective of this study was to analyze Cannabis by means of thermogravimetric analysis (TGA) in order to assess the capability of this technique to trace the geographical origin of Cannabis cultivated in Colorado, United States of America. TGA appears to be sensitive enough to detect the degradation/decarboxylation of cannabinoids and terpenes, at least to some extent; also, the degradation of cellulose, hemicellulose and lignin was indicated. Overall, the temperature ranges we analyzed using linear discriminant analysis showed high accuracies, with the 200 to 300 °C and 600 to 700 °C ranges achieving 100% accuracy.
大麻，即干燥和研磨后的大麻属植物，是世界上消费最多的非法药物。其使用会对人类健康造成许多不良和危险影响。在许多国家，大麻的药用或合法娱乐用途也在增加。这些事实使得可追溯性方法变得越来越重要，无论是用于法医学用途，如根除毒品贩运，还是用于合法药用大麻的质量控制目的。因此，本研究的目的是通过热重分析（TGA）对大麻进行分析，以评估该技术追踪在美国科罗拉多州种植的大麻地理来源的能力。热重分析似乎足够灵敏，至少在一定程度上能够检测大麻素和萜类化合物的降解/脱羧反应；此外，还表明了纤维素、半纤维素和木质素的降解。总体而言，我们使用线性判别分析所分析的温度范围显示出很高的准确率，200至300°C和600至700°C范围的准确率达到了100%。
