Institute of Biology, Leiden University, The Netherlands.
Inhal Toxicol. 2009 Nov;21(13):1108-12. doi: 10.3109/08958370902748559.
Cannabis sativa is a well-known recreational drug and, as such, a controlled substance of which possession and use are illegal in most countries of the world. Due to the legal constraints on the possession and use of C. sativa, relatively little research on the medicinal qualities of this plant has been conducted. Interest in the medicinal uses of this plant has, however, increased in the last decades. The methods of administration for medicinal purposes are mainly through oral ingestion, smoking, and nowadays also inhalation through vaporization. During this study the commercially available Volcano vaporizing device was compared with cannabis cigarette smoke. The cannabis smoke and vapor (obtained at different temperatures) were quantitatively analyzed by high-performance liquid chromatography (HPLC). In addition, different quantities of cannabis material were also tested with the vaporizer. The cannabinoids:by-products ratio in the vapor obtained at 200 degrees C and 230 degrees C was significantly higher than in the cigarette smoke. The worst ratio of cannabinoids:by-products was obtained from the vaporized cannabis sample at 170 degrees C.
大麻是一种众所周知的消遣性药物，因此，在世界上大多数国家，拥有和使用大麻都是非法的。由于对大麻的拥有和使用存在法律限制，因此对这种植物的药用特性进行的研究相对较少。然而，在过去几十年中，人们对这种植物的药用用途越来越感兴趣。药用给药方法主要通过口服、吸烟，现在也通过蒸发吸入。在这项研究中，将市售的 Volcano 汽化装置与大麻香烟烟雾进行了比较。通过高效液相色谱法（HPLC）对大麻烟雾和蒸汽（在不同温度下获得）进行了定量分析。此外，还使用汽化器对不同数量的大麻材料进行了测试。在 200 度和 230 度获得的蒸汽中的大麻素：副产物的比例明显高于香烟烟雾中的比例。在 170 度汽化的大麻样本中获得的大麻素：副产物的比例最差。
