Chromaleont s.r.l., c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, viale Annunziata, 98168, Messina, Italy..
Chromaleont s.r.l., c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, viale Annunziata, 98168, Messina, Italy.
J Chromatogr A. 2021 Jan 25;1637:461864. doi: 10.1016/j.chroma.2020.461864. Epub 2020 Dec 30.
The global Cannabis Sativa market, including essential oils, foods, personal-care products, and medical formulations has gained much attention over the last years due to the favorable regulatory framework. Undoubtedly, the enormous interest about cannabis cultivation mainly derives from the well-known pharmacological properties of cannabinoids and terpenes biosynthesized by the plants. In this review, the most recently used analytical methodologies for detecting both cannabinoids and terpenes are described. Well-established and innovative extraction protocols, and chromatographic separations, such as GC and HPLC, are reviewed highlighting their respective advantages and drawbacks. Lastly, GC × GC techniques are also reported for accurate identification and quantification of terpenes in complex cannabis matrices.
近年来，由于有利的监管框架，包括精油、食品、个人护理产品和医疗配方在内的全球大麻素市场备受关注。毫无疑问，人们对大麻种植的浓厚兴趣主要源于植物中生物合成的大麻素和萜烯的众所周知的药理学特性。在这篇综述中，描述了最近用于检测大麻素和萜烯的分析方法。综述了成熟和创新的提取方案以及色谱分离，如 GC 和 HPLC，并强调了它们各自的优缺点。最后，还报告了 GC×GC 技术在复杂大麻基质中萜烯的准确鉴定和定量。
