Division of Nursing, Florence Nightingale Faculty of Nursing, Istanbul University-Cerrahpaşa, Istanbul, Turkey.
Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Neurourol Urodyn. 2021 Aug;40(6):1661-1669. doi: 10.1002/nau.24733. Epub 2021 Jun 26.
Sexual dysfunction (SD) is common in female patients with multiple sclerosis (MS) reporting overactive bladder (OAB) symptoms. The aim of the study was to evaluate the effects of transcutaneous tibial nerve stimulation (TTNS) and pelvic floor muscle training (PFMT) with biofeedback on SD in female patients with MS reporting OAB symptoms.
Patients with overactive bladder and SD were allocated to receive TTNS or PFMT daily. Overactive bladder symptoms, sexual functions, and sexual quality of life were assessed at baseline and 6 weeks. Female Sexual Function Index (FSFI), Overactive Bladder Questionnaire (OABv-8), and Sexual Quality of Life-Female (SQoL-F) questionnaires were used.
Thirty patients (TTNS = 10, PFMT = 20) were included in the study. Compared to baseline, total FSFIOABv-8, and SQoL-F scores improved in both TTNS (p = 0.005, p = 0.011, p = 0.444, respectively) and PFMT (p = 0.002, p = 0.001, p = 0.001, respectively) groups. Between-group comparisons did not show any significant differences.
This study demonstrates the efficacy of both TTNS and PFMT for improving sexual function in female MS patients with OAB symptoms, but did not show superiority of any particular method. Further studies are required to investigate the differences between these two non-invasive methods.
患有多发性硬化症(MS)并伴有膀胱过度活动症(OAB)症状的女性患者常发生性功能障碍(SD)。本研究旨在评估经皮胫神经刺激(TTNS)和伴有生物反馈的盆底肌训练(PFMT)对伴有 OAB 症状的 MS 女性患者 SD 的影响。
将患有 OAB 和 SD 的患者分配至每日接受 TTNS 或 PFMT。在基线和 6 周时评估 OAB 症状、性功能和性生活质量。使用女性性功能指数(FSFI)、膀胱过度活动症问卷(OABv-8)和女性性生活质量问卷(SQoL-F)进行评估。
本研究共纳入 30 例患者(TTNS 组 10 例,PFMT 组 20 例)。与基线相比,TTNS 组(p=0.005,p=0.011,p=0.444)和 PFMT 组(p=0.002,p=0.001,p=0.001)的总 FSFI、OABv-8 和 SQoL-F 评分均有所改善。组间比较无显著差异。
本研究表明 TTNS 和 PFMT 均能有效改善伴有 OAB 症状的 MS 女性患者的性功能,但并未显示任何特定方法的优势。需要进一步研究来探讨这两种非侵入性方法之间的差异。