Physiotherapy Department, Western Health, Melbourne, Victoria, Australia; Allied Health Department, Ballarat Health Services, Ballarat, Victoria, Australia; Discipline of Physiotherapy, University of Canberra, Canberra, Australian Capital Territory, Australia; Prehab, Activity, Cancer, Exercise, Survivorship Research Group, University of Canberra, Canberra, Australian Capital Territory, Australia.
Pelvic Floor Exercise, Sunshine Coast, Queensland, Australia.
Neuromodulation. 2022 Dec;25(8):1086-1096. doi: 10.1016/j.neurom.2022.04.034. Epub 2022 Jun 8.
Overactive bladder (OAB) is a condition that has physical, social, psychosocial, and financial impacts. Transcutaneous tibial nerve stimulation (TTNS) is a modality that stimulates the nerve root fibers of L5-S3, the same spinal segments of the parasympathetic nervous system as the bladder. This scoping review aims to identify current literature available on the feasibility and outcomes of TTNS as a first-line treatment option for OAB.
A scoping review of six electronic data bases was performed to identify full-text articles from 2015 that explored the impact of TTNS on OAB and bladder dysfunction in people aged >18 years.
A total of 15 articles met the inclusion criteria. TTNS was compared with sham treatment, parasacral stimulation, pelvic floor muscle training (PFMT), anticholinergic medication, and percutaneous tibial nerve stimulation (PTNS). Heterogeneity in treatment application and parameters existed, with variations in treatment duration, frequency of use, and treatment settings such as pulse width (μs) and frequency (Hz). Results indicated that TTNS has efficacy equal to PFMT and PTNS in the management of OAB; however, it is not as efficacious as anticholinergic medication.
TTNS is a promising first-line management option for people with OAB, particularly in the older population and for those with neurogenic bladder. It can provide symptomatic relief from urinary incontinence, frequency, urgency, and nocturia, while avoiding the bothersome side effects of more invasive or pharmaceutical therapies. Heterogeneity in treatment parameters limits generalizability and translation of the most appropriate clinical application and should be considered in future trials.
膀胱过度活动症(OAB)会对患者造成身体、社会、心理社会和经济方面的影响。经皮胫神经刺激(TTNS)是一种刺激 L5-S3 神经根纤维的方法,与膀胱相同的脊髓节段为副交感神经系统。本范围性综述旨在确定目前关于 TTNS 作为 OAB 一线治疗选择的可行性和结果的文献。
对六个电子数据库进行了范围性综述,以确定 2015 年以来探讨 TTNS 对 18 岁以上人群 OAB 和膀胱功能障碍影响的全文文章。
共有 15 篇文章符合纳入标准。TTNS 与假治疗、骶神经刺激、盆底肌训练(PFMT)、抗胆碱能药物和经皮胫神经刺激(PTNS)进行了比较。治疗应用和参数存在异质性,治疗持续时间、使用频率以及治疗设置(如脉冲宽度(μs)和频率(Hz))存在差异。结果表明,TTNS 在 OAB 管理中与 PFMT 和 PTNS 具有同等疗效;然而,它不如抗胆碱能药物有效。
TTNS 是 OAB 患者的一种有前途的一线治疗选择,特别是在老年人群和神经源性膀胱患者中。它可以缓解尿失禁、尿频、尿急和夜尿症的症状,同时避免更具侵入性或药物治疗的烦扰副作用。治疗参数的异质性限制了其普遍性和最适当临床应用的转化,应在未来的试验中加以考虑。