Suppr超能文献

随机试验用肥皂 - 新生儿的皮肤会发生什么?

Randomized trial with soaps - what happens to a newborn baby's skin?

机构信息

Universidade Federal do Paraná, Departamento de Pediatria, Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Curitiba, PR, Brazil.

Universidade Federal do Paraná, Departamento de Pediatria, Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Curitiba, PR, Brazil.

出版信息

J Pediatr (Rio J). 2022 Mar-Apr;98(2):204-211. doi: 10.1016/j.jped.2021.05.005. Epub 2021 Jun 23.

Abstract

OBJECTIVE

Evaluate the effectiveness of a children's soap with physiological pH in maintaining cutaneous pH and moisture of the newborn (NB)'s skin after the first bath.

METHODS

Randomized, controlled and double-blind clinical trial in a rooming-in of a tertiary maternity hospital in southern Brazil with 204 newborns > 34 gestational weeks. Gestational and obstetric history was evaluated, and newborns were randomized into two groups according to the product applied in the bath: the control group (CG), which used common liquid soap with pH 7.0 and experimental group (EG), which used children's liquid soap with pH 5.8. Evaluation was made immediately before and after bath with skin pH measurement, corneometry and clinical parameters (erythema, scaling and moisture), on the forehead, abdomen and thigh.

RESULTS

There was no difference between groups regarding gestational, obstetric and family history (p > 0.05). In CG, skin pH increased in the abdomen and thigh (p < 0.05). In EG there was an improvement in clinical parameters after bathing with: increased moisture, less erythema and less scaling (p < 0.05). On the forehead, there was a significant increase in pH after bathing (p < 0.001) similar in both groups, although no use of soap. There was no difference in corneometry between groups after bathing.

CONCLUSION

Children's liquid soap with physiological pH maintained the acidic skin pH and moisture of the newborn's skin after the first bath, which reinforces the importance of using products with physiological pH in the hygiene of newborns. Registration number RBR-9ky84vd.

摘要

目的

评估一款具有生理 pH 值的儿童肥皂在新生儿(NB)第一次洗澡后维持皮肤 pH 值和水分的效果。

方法

这是一项在巴西南部一家三级妇产医院的母婴同室病房中进行的随机、对照、双盲临床试验,共有 204 名胎龄超过 34 周的新生儿参与。评估了妊娠和产科史,并根据洗澡时使用的产品将新生儿随机分为两组:对照组(CG)使用 pH 值为 7.0 的普通液体肥皂,实验组(EG)使用 pH 值为 5.8 的儿童液体肥皂。在洗澡前和洗澡后立即进行皮肤 pH 值测量、皮肤角质层水分测量和临床参数(红斑、鳞屑和水分)评估,评估部位为前额、腹部和大腿。

结果

两组在妊娠、产科和家族史方面无差异(p>0.05)。在 CG 组中,腹部和大腿的皮肤 pH 值升高(p<0.05)。在 EG 组中,洗澡后临床参数有所改善:水分增加,红斑和鳞屑减少(p<0.05)。在前额,尽管没有使用肥皂,但洗澡后 pH 值显著升高(p<0.001),两组之间相似。洗澡后两组间的皮肤角质层水分测量值无差异。

结论

具有生理 pH 值的儿童液体肥皂可维持新生儿皮肤的酸性 pH 值和水分,这强调了在新生儿的卫生保健中使用具有生理 pH 值的产品的重要性。注册号 RBR-9ky84vd。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66a2/9432187/32f507468ef4/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验