Abudouaini Haimiti, Huang Chengyi, Liu Hao, Wang Beiyu, Ding Chen, Wu Tingkui, Hong Ying, Meng Yang
Department of Orthopedic Surgery, West China Hospital, Sichuan University, China.
Department of Orthopedic Surgery, West China Hospital, Sichuan University, China.
Clin Neurol Neurosurg. 2021 Aug;207:106759. doi: 10.1016/j.clineuro.2021.106759. Epub 2021 Jun 11.
Cervical disc replacement (CDR) has been established as an alternative to anterior cervical discectomy and fusion (ACDF) for treating cervical degenerative pathologies over the past decade. However, swallowing difficulties challenge patient safety due to the increased risk of malnutrition, dehydration and aspiration pneumonia after CDR. Currently, there are limited studies focusing on the incidences, severity and associated risk factors for dysphagia after CDR. This paucity, therefore, necessitated this retrospective study on post-operative dysphagia after one- and two-level CDR.
One hundred and fourteen patients underwent one-level CDR and forty eight patients underwent two-level CDR were recruited with a mean follow-up of 21 months (ranging from 14 to 30 months). The prevalence and severity of dysphagia was evaluated by the Bazaz grading system during the follow-up time. Regression analyses were done to identify risk factors associated with post-operative dysphagia after CDR.
The overall dysphagia occurrences in the one- and two-level CDR groups were 17.54% and 35.41% at week one, 12.28% and 25% after one month, 9.65% and 18.75% after three months, 6.14% and 14.58% after six months, 4.39% and 6.25% after one year, and 3.51% and 4.17% at the final follow-up, respectively. The identified risk factors for dysphagia after CDR were advanced age, C4/5 surgery, two-level surgery, dC2-C7 angle ≥ - 5° and ≥ 6 mm changes in the prevertebral soft tissue swelling (dPSTS).
The patients who experienced two-level CDR may have poor swallowing functions in the early post-operative term. However, these patients also can recover well with increasing length of follow-up. In addition, patients with advanced age, C4/5 surgery, dC2-C7 angle ≥ - 5° and ≥ 6 mm changes in dPSTS may prone to occur dysphagia after CDR.
在过去十年中,颈椎间盘置换术(CDR)已成为治疗颈椎退行性病变的一种替代前路颈椎间盘切除融合术(ACDF)的方法。然而,吞咽困难对患者安全构成挑战,因为CDR后营养不良、脱水和吸入性肺炎的风险增加。目前,关注CDR后吞咽困难的发生率、严重程度及相关危险因素的研究有限。因此,这种匮乏促使我们对单节段和双节段CDR术后吞咽困难进行这项回顾性研究。
招募了114例行单节段CDR的患者和48例行双节段CDR的患者,平均随访21个月(14至30个月)。在随访期间,采用Bazaz分级系统评估吞咽困难的发生率和严重程度。进行回归分析以确定与CDR术后吞咽困难相关的危险因素。
单节段和双节段CDR组在术后第1周吞咽困难的总体发生率分别为17.54%和35.41%,1个月后分别为12.28%和25%,3个月后分别为9.65%和18.75%,6个月后分别为6.14%和14.58%,1年后分别为4.39%和6.25%,最后随访时分别为3.51%和4.17%。确定的CDR后吞咽困难的危险因素为高龄、C4/5节段手术、双节段手术、dC2-C7角≥ -5°以及椎体前软组织肿胀(dPSTS)变化≥6 mm。
经历双节段CDR的患者在术后早期吞咽功能可能较差。然而,随着随访时间的延长,这些患者也能恢复良好。此外,高龄、C4/5节段手术、dC2-C7角≥ -5°以及dPSTS变化≥6 mm的患者在CDR后可能更容易发生吞咽困难。