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对比使用 Zero-P 植入系统行单节段与双节段前路颈椎间盘切除融合术患者的术后报告吞咽困难。

Comparison of Patient-Reported Postoperative Dysphagia in Patients Undergoing One-Level Versus Two-Level Anterior Cervical Discectomy and Fusion with the Zero-P Implant System.

机构信息

Department of Orthopedic Surgery, West China Hospital, No. 37 Guo Xue Xiang Rd., Chengdu, 610041, Sichuan, China.

出版信息

Dysphagia. 2021 Aug;36(4):743-753. doi: 10.1007/s00455-020-10197-w. Epub 2021 Jan 2.

Abstract

To investigate whether dysphagia differs between one-level and two-level anterior cervical discectomy and fusion (ACDF) with the Zero Profile (Zero-P) Implant System. A retrospective analysis of 208 patients who underwent ACDF with the Zero-P Implant System and had at least one year of follow-up was performed from January 2013 to December 2018. The patients were divided into two groups based on the number of operated levels (one-level group, N = 86; two-level group, N = 122). Dysphagia was assessed based on the Bazaz grading system. The incidence of dysphagia and the severity of dysphagia at each follow-up were compared between the two groups. The patients were divided into two groups (nondysphagia group, N = 160; dysphagia group, N = 48), and covariates were obtained for multivariate analysis, including demographic parameters, surgical parameters, and radiographic parameters. The results showed that the incidence and severity of postoperative dysphagia in the two-level group were significantly greater at 1 week, 1 month and 3 months postoperatively than those in the one-level group. The results of ordinal logistic regression showed that older age, two-level surgery, greater prevertebral soft tissue swelling (PSTS) and the difference between the postoperative and preoperative C angle (dCA) were significantly associated with a higher incidence of dysphagia after ACDF with the Zero-P. Two-level ACDF with the Zero-P can result in a significantly greater incidence and severity of transient postoperative dysphagia. Older age, greater PSTS and the dCA were also associated with postoperative dysphagia after ACDF with the Zero-P.

摘要

为了探讨 Zero Profile (Zero-P) 植入系统单节段与双节段颈椎前路椎间盘切除融合术(ACDF)术后吞咽困难是否存在差异,对 2013 年 1 月至 2018 年 12 月期间接受 Zero-P 植入系统 ACDF 治疗且随访时间至少 1 年的 208 例患者进行回顾性分析。根据手术节段数(单节段组,N=86;双节段组,N=122)将患者分为两组。采用 Bazaz 分级系统评估吞咽困难情况,比较两组患者在各随访时间点的吞咽困难发生率和严重程度。将患者分为两组(无吞咽困难组,N=160;吞咽困难组,N=48),并进行多变量分析,获得包括人口统计学参数、手术参数和影像学参数在内的协变量。结果显示,双节段组术后 1 周、1 个月和 3 个月时的吞咽困难发生率和严重程度均明显高于单节段组。有序逻辑回归分析结果显示,年龄较大、双节段手术、术前椎体前软组织肿胀(PSTS)较大以及术后与术前 C 角差值(dCA)较大与 Zero-P 辅助 ACDF 术后吞咽困难发生率较高显著相关。与单节段相比,Zero-P 辅助双节段 ACDF 可显著增加术后暂时性吞咽困难的发生率和严重程度。此外,年龄较大、PSTS 较大和 dCA 也与 Zero-P 辅助 ACDF 术后吞咽困难有关。

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