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膀胱癌根治术后的原位尿流改道术:过去十年的经验教训。

Orthotopic urinary diversions after radical cystectomy for bladder cancer: lessons learned last decade.

机构信息

Department of Urology, RadboudUMC, Nijmegen, The Netherlands.

Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

出版信息

Curr Opin Urol. 2021 Nov 1;31(6):580-585. doi: 10.1097/MOU.0000000000000909.

Abstract

PURPOSE OF REVIEW

Orthotopic urinary diversion (OUD), or neobladder, is believed to be the gold standard for surgical bladder reconstruction following radical cystectomy though it is performed far less often than ileal conduits. As both a continent and intracavitary diversion, OUDs offer unique advantages for patients. Their utilization has decreased overall though, especially with the advent of robotic surgery. In this review, we will cover patient selection for OUD, functional outcomes (i.e., continence, sexual activity, quality of life [QoL]), and robotic orthotopic diversions.

RECENT FINDINGS

OUDs have seen a proportionally greater decline in utilization compared with ileal conduits as the number of robotic radical cystectomies being performed with intracorporeal diversions increases. Multiple robotic series have demonstrated less perioperative blood loss and shorter hospital stays when compared with the open approach though operative times are longer, the learning curve is steeper, and overall costs may be higher in some settings. Perioperative safety and short-term oncological outcomes appear comparable. Since robotic OUDs are relatively new, functional outcomes are not yet well established. Patient satisfaction with urinary diversion is associated with informed decision-making tailored to the patient. A thorough understanding of expected short- and long-term functional outcomes and the care required to maintain an OUD improves QoL and satisfaction with diversion choice.

SUMMARY

Given the potential advantages of OUD, its decreasing use is a remarkable trend. Shared decision-making and a patient-centered approach should be used when selecting the type of urinary diversion.

摘要

目的综述

原位尿流改道术(OUD),或新膀胱,被认为是根治性膀胱切除术后重建膀胱的金标准,尽管其实施频率远低于回肠导管术。作为一种有控和腔内尿流改道术,OUD 为患者提供了独特的优势。尽管随着机器人手术的出现,其总体利用率有所下降。在这篇综述中,我们将讨论 OUD 的患者选择、功能结果(即控尿、性行为、生活质量[QoL])和机器人原位尿流改道术。

最新发现

与回肠导管术相比,随着进行腔内尿流改道术的机器人根治性膀胱切除术数量的增加,OUD 的使用比例呈下降趋势。多项机器人系列研究表明,与开放式手术相比,其围手术期出血量更少,住院时间更短,尽管手术时间更长,学习曲线更陡峭,在某些情况下,总费用可能更高。围手术期安全性和短期肿瘤学结果似乎相似。由于机器人 OUD 相对较新,其功能结果尚未得到充分确立。尿流改道患者的满意度与针对患者的知情决策有关。充分了解预期的短期和长期功能结果以及维持 OUD 所需的护理可以提高 QoL 和对尿流改道选择的满意度。

总结

鉴于 OUD 的潜在优势,其使用减少是一个显著的趋势。在选择尿流改道类型时,应采用共同决策和以患者为中心的方法。

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