糖尿病患者有无非增殖性糖尿病视网膜病变的视力和对比敏感度研究。

Study of visual acuity and contrast sensitivity in diabetic patients with and without non-proliferative diabetic retinopathy.

机构信息

Department of Ophthalmology, James Cook University Hospital, Middlerbrough, UK.

Department of Ophthalmology, Santiago de Compostela University Medical School, C/ Ramon Baltar s/n, 15706, Santiago de Compostela-La Coruña, Spain.

出版信息

Int Ophthalmol. 2021 Nov;41(11):3587-3592. doi: 10.1007/s10792-021-01930-x. Epub 2021 Jun 27.

DOI:10.1007/s10792-021-01930-x

PMID:34176010

Abstract

PURPOSE

To analyze high and low contrast visual acuity and contrast sensitivity in diabetic patients without clinically significant macular edema associated or not with non-proliferative diabetic retinopathy.

METHODS

Cross-sectional study of 368 eyes of 368 patients classified into three groups: a) disease-free patients, b) patients with diabetes mellitus (DM) without diabetic retinopathy, c) DM patients with non-proliferative diabetic retinopathy. All patients underwent a complete ophthalmological examination that included high and low contrast visual acuity with 1.25%, 2.5% and 5% contrast chart and Pelli-Robson type contrast sensitivity test.

RESULTS

We observed no statistically significant differences regarding age, intraocular pressure, duration of diabetes or high contrast visual acuity. The eyes of patients with non-proliferative diabetic retinopathy had worse contrast sensitivity (p = 0.03, in both cases) and low contrast visual acuity at 1.5% (p = 0.03 and p = 0.01), 2.5% (p = 0.01, in both cases) and 5% (p = 0.02 and p = 0.04) than patients free of disease or without diabetic retinopathy.

CONCLUSIONS

Analysis of contrast sensitivity and low contrast visual acuity could be considered as markers of visual function impairment in the eyes of patients with non-proliferative diabetic retinopathy.

摘要

目的

分析无临床显著黄斑水肿的糖尿病患者以及伴有或不伴有非增殖性糖尿病性视网膜病变的糖尿病患者的高、低对比度视力和对比敏感度。

方法

对 368 名患者的 368 只眼进行了横断面研究，这些患者被分为三组：a）无疾病患者，b）无糖尿病性视网膜病变的糖尿病患者，c）伴有非增殖性糖尿病性视网膜病变的糖尿病患者。所有患者均接受了完整的眼科检查，包括使用 1.25%、2.5%和 5%对比度图表以及 Pelli-Robson 型对比敏感度测试进行高、低对比度视力检查。

结果

我们观察到年龄、眼内压、糖尿病持续时间或高对比度视力方面无统计学显著差异。患有非增殖性糖尿病性视网膜病变的患者的对比敏感度较差（p=0.03，两种情况下），并且在 1.5%（p=0.03 和 p=0.01）、2.5%（p=0.01，两种情况下）和 5%（p=0.02 和 p=0.04）的低对比度视力低于无疾病或无糖尿病性视网膜病变的患者。