Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.
Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.
Clin Lymphoma Myeloma Leuk. 2021 Sep;21(9):580-597. doi: 10.1016/j.clml.2021.05.016. Epub 2021 May 29.
With the Food and Drug Administration approval of 9 agents for different acute myeloid leukemia (AML) indications, the prognosis and management of AML is evolving rapidly. Herein, we review the important milestones in the history of AML research and therapy, discuss insights regarding prognostic assessment and prediction of treatment outcome, detail practical supportive care measures, and summarize the current treatment landscape and areas of evolving research.
随着食品和药物管理局(FDA)批准了 9 种用于不同急性髓细胞白血病(AML)适应证的药物,AML 的预后和治疗正在迅速发展。在此,我们回顾了 AML 研究和治疗的重要里程碑,讨论了预后评估和治疗结果预测方面的新认识,详细介绍了实用的支持性护理措施,并总结了当前的治疗现状和不断发展的研究领域。